Product name: Arteannuin B
Synonym name: 107172-37-2
Catalogue No.: BP1581
Cas No.: 50906-56-4
Formula: C₁₅H₂₀O₃
Mol Weight: 248.322
Botanical Source: Constit. of Artemisia annua
Physical Description: Powder
Type of Compound: Sesquiterpenoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.

Description:

Arteannuin B and artemisinic acid are biogenetic precursors of artemisinin, an important antimalarial produced by the herb Artemisia annua, they are active against different bacteria and certain fungal species. Arteannuin B has potential antimalarialand antitumor activity.

References:

Yao Xue Xue Bao. 1992;27(4):317-20.    

Derivatives of arteannuin B with antileukemia activity   

METHODS AND RESULTS:

Arteannuin B (I) was converted to hydroxy lactones (VII, VIII) by a mixture of formic acid and sulfuric acid. Compound VI and Compound VII both showed activity against leukemia P 388 cell in vitro. The rate of growth inhibition were 97.5% and 11.8% for (VI) and 80% and 52.6% for (VII) at the concentration of 10 and 1 micrograms/ml respectively. 

CONCLUSIONS:

It seems that the antileukemia activity of 6-membered lactone is higher than that of 5-membered and the methylene group is necessary for the antileukemia activity.    

Current Science, 2000 , 78 (6) :709-713.    

Antimicrobial activity of artemisinin and its precursors.   

Artemisinic acid and Arteannuin B are biogenetic precursors of artemisinin, an important antimalarial produced by the herb Artemisia annua. These compounds have been screened for antimicrobial activity against a range of organisms. 

CONCLUSIONS:

All the three compounds are active against different bacteria and certain fungal species. 

HPLC of Arteannuin B

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃