Product name: Jujuboside B
Synonym name:
Catalogue No.: BP0814
Cas No.: 55466-05-2
Formula: C52H84O21
Mol Weight: 1045.22
Botanical Source: seeds of Zizyphus jujuba (Chinese date)
Physical Description: White powder
Type of Compound: Triterpenoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Jujuboside B is one of the saponins isolated from the seeds of Zizyphus jujuba var, has
antitumor activity and the underlying mechanism via induction of apoptosis and autophagy.[1]
Jujuboside B has potent inhibitory effects on collagen-, thrombin-, AA-, and ADP-induced aggregation, also exhibits superior protection on thromboembolic model, it has a significant inhibitory effect on collagen-induced thromboxane A2 production in rat platelets; suggest that it be considered as components of preventive and therapeutic herbal drugs targeting cardiovascular diseases associated with platelet hyperaggregation.[2]
Jujuboside B reduces vascular tension endothelium-dependently by increasing Ca2+Influx and activating endothelial nitric oxide synthase, it is a natural compound with new pharmacological effects on improving endothelial dysfunction and treating vascular diseases.[3]
References:
[1] Xu M Y, Lee S Y, Kang S S, et al. J Nat Prod, 2014, 77(2):370-6.
[2] Seo E J, Lee S Y, Kang S S, et al. Phytother Res, 2013, 27(6):829-34.
[3] Zhao Y, Zhang X, Li J, et al. Plos One, 2016, 11(2)):e0149386.
[4] X Y Li, Gao Z, An X N, et al. Food Sci Technol, 2014(12):299-302.
HPLC of Jujuboside B
HNMR of Jujuboside B
Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃
