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Antioxidant and Anti-malarial Properties of Catechins

Journal name:BRIT J SPORT MED.
Literature No.:
Literature Url: http://search.proquest.com/openview/ba61d908db90345377390f05b3174f49/1?pq-origsite=gscholar
Date publication:5.7 (2015)


Aims: This research was performed to evaluate the antioxidant and anti malarial activities of

various catechins including catechin (C), epicatechin (EC), catechin-gallate (CG), gallocatechingallate (GCG), epigallocatechin (EGC), epicatechin-gallate (ECG), epigallocatechin gallate (EGCG).

Study Design: The antioxidant activity was measured by 1,1-diphenyl-2-picryl-hydrazyl (DPPH)

scavenging activity and anti-malarial activity was determined by In vitro assay against P. Falciparum culture, antioxidant activity was analyzed using linear regression analysis, and was continued by determining Inhibitory Concentration 50 (IC50). The anti-malarial activity was analyzed by probit analysis and IC50 determination.

 catechin hydrate (C), epicatechin (EC), cathecingallate (CG), gallocatechin (GC), (-)-epicatechin gallate (ECG), epigallocatechin (EGC), gallocatechingallate (GCG),(-)-epigallocatechin gallate (EGCG) purchased from Biopurify Phytochemicals Ltd,