Product name: Sesamolin
Synonym name:
Catalogue No.: BP1298
Cas No.: 526-07-8
Formula: C₂₀H₁₈O₇
Mol Weight: 370.357
Botanical Source: sesame oil and Justicia orbiculata
Physical Description: White powder
Type of Compound: Lignans

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.

Descriptions:
Sesaminol possesses antioxidative activity, can inhibit lipid peroxidation in rat liver and kidney.[1]
Sesamolin has protective effect on hypoxic neuronal and PC12 cells, it might be related to suppression of ROS generation and MAPK activation.[2]
Sesamolin can inhibit proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. [3]
Sesamolin has protective effects on murine BV-2 microglia cell line under hypoxia, the mechanism involves inhibition of MAPK pathways and apoptosis through scavenging of ROS in hypoxia-stressed BV-2 cells.[4]
Sesamolin exerts effective neuroprotection against cerbral ischemia.[5]

References:
[1] Kang M H, Naito M, Tsujihara N, et al. J Nut, 1998, 128(6):1018-22.
[2] Hou C W, Huang H M, Tzen J T C, et al. J Neurosci Res, 2003, 74(1):123–33.
[3] Miyahara Y, Hibasami H, Katsuzaki H, et al. Int J Mol Med, 2001, 7(7):369-71.
[4] Hou C W, Wu C C, Yang C H, et al. Neurosci Lett, 2004, 367(1):10-3.
[5] Cheng F C, Jinn T R, Hou R C W, et al. Int J Biomed Sci Ljbs, 2006, 2(3):284-8.
[6] Huang J. Journal of the Chinese Cereals & Oils Association, 2011, 26(01):120-3.

HPLC of Sesamolin

Storage conditions：Short-term storage at 2~8℃, long-term storage at -20 ~ -80℃