1、 Pharmacopoeia standard of pig tooth soap
This product is the dry sterile fruit of Gleditsia sinensis lam., a legume. Harvest in autumn, remove impurities and dry.
[properties] this product is cylindrical, slightly flat and curved, 5-11cm long and 0.7-1.5cm wide. Its surface is purplish brown or purplish brown, and is covered with gray white waxy powder. It is shiny after wiping, and has small warty protrusions and linear or reticular cracks. There are beak shaped style residues at the top and fruit stalk residue marks at the base. It is hard and brittle, easy to break, with brownish yellow section, loose middle, light green or light brownish yellow filaments, and occasionally underdeveloped seeds. It is slightly pungent and tastes sweet before spicy.
[identification] (1) the powder of this product is brownish yellow. The stone cells are numerous, oval, oblong or irregular in shape, with a diameter of 15-53 μ M. Most of the fibers are in bundles, with a diameter of 10-25 μ m, and the wall is slightly lignified. The surrounding cells contain calcium oxalate crystals and a few cluster crystals, forming crystal fibers; Square like sclerenchyma cells often accompany the fiber bundles. ; The diameter of cluster crystals is 6 ～ 14 μ M. There are many lignified parenchyma cells with obvious pits and grooves. The epidermal cells of the pericarp are reddish brown, with a polygonal appearance on the surface, thick walls, and granular cuticular texture on the surface.
(2) Take 1g of this product powder, add 8ml of ethanol, heat and reflux for 5 minutes, cool it and filter it. Take 0.5ml of the filtrate, put it in a small porcelain dish, evaporate it to dryness, cool it, add 3 drops of acetic anhydride, mix it well, add 2 drops of sulfuric acid along the wall of the dish, and it gradually turns red and purple.
(3) .
(4) Take 1g of the product powder, add 10ml of methanol, sonicate for 30 minutes, filter, evaporate the filtrate, add 10ml of water to dissolve the residue, add 10ml of ethyl acetate to shake for extraction, take ethyl acetate solution, evaporate to dryness, add 1ml of methanol to dissolve the residue, and use it as the test solution. . According to the test of thin-layer chromatography (general rule 0502), suck 10 μ l of each of the above two solutions, dot them on the same silica gel G thin-layer plate, use the lower layer solution of chloroform methanol water glacial acetic acid (18:1:0.6:0.2) as the developing agent, develop, take out, dry, spray 10% sulfuric acid ethanol solution, heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
[inspection] the moisture content shall not exceed 14.0% (the second method of general rule 0832).
.
Decoction pieces
[processing] remove impurities, wash and dry. Mash when needed.
[character], [identification], [inspection] are the same as medicinal materials.
[nature, taste and meridian tropism] spicy, salty and warm; There is little poison. Return to lung and large intestine channels.
[functions and indications] dispel phlegm and resuscitate, disperse nodules and reduce swelling. It is used for stroke, mouth shudder, coma, epilepsy, phlegm, obstruction of the orifice, throat obstruction, persistent phlegm, cough, expectoration, dry stool; External treatment carbuncle.
. For external use, use appropriate amount, blow nose and sneeze at the end of grinding or apply on the affected area at the end of grinding.
[note] it is forbidden for pregnant women and patients with hemoptysis and hematemesis.
.

2、 Chemical constituents of pig tooth soap

Pig tooth soap mainly contains various types of triterpenoid saponins, in addition to tanninsStigmasterol, sitosterol, trace elements, etc.

3、 Pharmacological effects of pig tooth soap

  1. .
    
  2. Its saponins can make the plasma membrane of Trichomonas vaginalis thin, and the plasma is exposed, causing the body to collapse.