Myrtle
Mimenghua
BUDDLEJAE FLOS
This product is the dried flower buds and inflorescences of buddieja officinalis maxim., a plant of the loganaceae family. .Mimenghua
BUDDLEJAE FLOS
[character] this product is mostly small branches of inflorescence with dense flower buds, in irregular cone shape, 1.5 ~ 3cm long. The surface is grayish yellow or brownish yellow, densely covered with fluff. The flower buds are short rod-shaped, slightly larger at the upper end, 0.3 ~ 1cm long and 0.1 ~ 0.2cm in diameter; the calyx is bell shaped, and the apex is 4-toothed; ; Stamens 4, inserted in the middle of corolla tube. . The smell is slightly fragrant, and the taste is slightly bitter and pungent.
[identification] the powder is brown. Non glandular hairs are usually 4-cell, with 2-cell rows at the base; The upper two cells are juxtaposed, and each cell is divided into two branches, each of which is 50-500 μ m long, with very thick walls and linear lumens. There are a few non glandular hairs on the upper surface of the corolla, which are single-cell, 38 ～ 600 μ m long, and the wall has many spiny protrusions. The pollen grains are spherical, 13-20 μ m in diameter, with smooth surface and three germination pores. ; The handle is extremely short.
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Chromatographic conditions and system suitability test octadecylsilane bonded silica gel was used as filler; ; The detection wavelength was 326nm. The number of theoretical plates should not be less than 1000 based on the peak of linarin.
Preparation of reference solution take an appropriate amount of linarin reference, weigh accurately, add methanol to make a solution containing 0.1mg of linarin per 1ml.
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The determination method is to precisely suck 10 μ l of the reference solution and 5 ～ 10 μ l of the test solution, inject them into the liquid chromatograph, and determine.
The content of linarin (c28h32o14) in this product shall not be less than 0.50%.
[nature, taste and meridian tropism] sweet, slightly cold. Return to liver meridian.
. It is used for redness, swelling and pain of the eyes, more tears and shame, the eyes have a film of opacity, the liver is weak, the eyes are dark, and the vision is dim.
[usage and dosage] 3 ~ 9g.
[storage] store in a ventilated and dry place to prevent moisture.
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Spikelets contain buddleosideRobininAnd other flavonoids.
3、 Pharmacological effects of Buddleja officinalis
Similar to quercetin, Robinia pseudoacacia has vitamin P-like effects. Oral administration of 25-100 mg / kg to mice can reduce formaldehyde induced inflammation; 50-100 mg / kg can also reduce the permeability and fragility of skin and small intestinal blood vessels. The tension of isolated rat small intestine caused by barium chloride, histamine, acetylcholine, etc. increases, and Robinia pseudoacacia has some antispasmodic effects. . Intravenous injection of 25 mg / kg to rabbits can slightly increase urine output (75%) within 25-30 minutes. For normal rats, it does not affect the sleep time caused by cyclohexbarbital, but for rats with carbon tetrachloride hepatitis, it can shorten the sleep time. Robinia pseudoacacia is not toxic, and the median lethal dose in mice is 933 mg / kg. In isolated mouse small intestine specimens, acetylcholine was used to induce spasm, and the antispasmodic effect of robiniatin was 75% of that of papaverine.