Aconite leaf
Caowuye
ACONITI KUSNEZOFFII FOLIUM
Caowuye
ACONITI KUSNEZOFFII FOLIUM
This product is a traditional Mongolian medicine. . Harvest when the leaves are luxuriant and the flowers are not in bloom in summer, remove impurities and dry in time.
[character] this product is often wrinkled, curled and broken. After flattening, the intact leaves are oval, 3-lobed, 5-12cm long and 10-17cm wide; grayish green or yellowish green; Middle lobe rhombic, acuminate, subpinnately cleft; ; Lobules lanceolate or ovate lanceolate. The upper surface is slightly pilose, and the lower surface is glabrous; The petiole is 2 ~ 6cm long and brittle. It is slightly salty and pungent.
[identification] (1) the appearance of this product: the vertical peripheral wall of the upper epidermal cells is microwave like bending, and some of the outer flat peripheral walls can see sparse cuticular texture; Non glandular hairs are single-cell, mostly sickle shaped, about 468 μ m long, 44 μ m in diameter, and have warty protrusions on the wall. The vertical wall of the lower epidermal cells was deeply wavy; .
(2) Take 5g of this product powder, add 25ml of trichloromethane, shake well, add 2ml of sodium carbonate test solution, shake for 30 minutes, filter, take 4ml of dilute hydrochloric acid to the filtrate, shake; ; Add 2 drops of silicotungstic acid test solution into the other tube to generate gray white precipitate.
[nature, taste and meridian tropism] pungent, astringent and flat; .
[functions and indications] it can clear away heat, detoxify and relieve pain. .
[usage and dosage] 1 ~ 1.2g, multi entry pill powder.
[note] pregnant women should use it with caution.
[storage] put it in a dry place.
2、 Chemical constituents of Aconitum kusnezoffii leaves
Aconitum kusnezoffii leaves contain alkaloids, the main components of which areAconitineIt also contains phenolic components, sugars and polysaccharides.
3、 Pharmacological effects of Aconitum kusnezoffii leaves.The study of the pharmacological effects of Aconitum kusnezoffii leaves on the rats in the experiment group of the Second Affiliated Hospital of the people's Republic of China in the period of 1-2
1. anti inflammatory effect ; 0.05% total alkaloid of Aconitum kusnezoffii leaves has a very significant anti-inflammatory effect at the 4th hour, and the swelling elimination rate can reach about 3.5%. In the experiment, it was also found that the preparation of Aconitum kusnezoffii leaves can increase the appetite, health and vitality, and weight gain of rats. Among them, the total alkaloids of Aconitum kusnezoffii leaves were the most significant.
2. analgesic effect 2.5% Aconitum kusnezoffii leaf decoction has a quite significant inhibitory effect on acetic acid-induced "writhing movement" in mice. The total alkaloids of Aconitum kusnezoffii leaves at 2.5mg/kg also produced almost the same effect.
3. 20% and 50% toxic Decoction of Aconitum kusnezoffii leaves were given to mice by gavage, and the maximum dose of Aconitum kusnezoffii was up to 15mg / kg. No toxic reaction was found, which could increase the appetite and weight of animals. The LD50 of total alkaloids of Aconitum kusnezoffii leaves in mice was 15mg / kg by gavage.