1、 Pharmacopoeia standard of pangdahai
.
[properties] this product is spindle shaped or oval, 2-3cm long, 1-1.5cm in diameter. The apex is blunt, the base is slightly pointed and crooked, and has a light colored round navel. . The outer seed coat is extremely thin, brittle and easy to fall off. The seed coat in the middle layer is thick, dark brown, loose and fragile, and expands into spongy shape in case of water. Scattered resin like dots can be seen on the section. The inner seed coat can be peeled off from the middle seed coat, slightly leathery, with 2 pieces of hypertrophic endosperm inside, broadly ovoid; Cotyledons 2, thin, close to the inner side of endosperm, as large as endosperm. .
[identification] (1) take several capsules of this product and place them in a beaker. Add a proper amount of boiling water. After several minutes, it will absorb water and expand into a brown translucent sponge.
(2) This product is brown in powder. The surface of seed coat epidermal cells is square or pentagonal, containing light brownish yellow substances, and the vertical wall is Beaded thickened, and the stomata are flat axis. The seed coat parenchyma cells were irregular stars, with single striated pores, and some contained light brown yellow substances. There are many glandular hairs, the head is scalloped or glandular squamous, 8-20 cells, containing brown secretions, and the stalk single cell is extremely short. The inner seed coat grid cells are pale yellow, with polygonal surface and brownish yellow contents in the lumen.
[inspection] the moisture content shall not exceed 16.0% (the second method of general rule 0832).
Aflatoxin was determined according to the aflatoxin assay (general rule 2351).
Take about 5g of this product powder (passing through No. 2 screen), accurately weigh it, add 3G of sodium chloride, measure and calculate according to the preparation method of the test article under the aflatoxin determination method.
The content of aflatoxin B1 should not exceed 5 μ g per 1000g, and the total content of aflatoxin G2, aflatoxin G1, aflatoxin B2 and aflatoxin B1 should not exceed 10 μ G.
[nature, taste and meridian tropism] sweet, cold. Return to lung and large intestine channels.
[functions and indications] it can clear away heat and moisten the lungs, soothe the throat and open the voice, moisten the intestine and relieve constipation. It is used for lung heat and hoarseness, dry cough without phlegm, sore throat, heat knot and closed stool, headache and red eyes.
[usage and dosage] 2-3 tablets, taken in boiling water or decocted.
[storage] put it in a dry place to prevent mold and moth.

2、

Containing D-galactose, L-rhamnose, sucrose, 2,4-dihydroxybenzoic acidβ - sitosterolandCarotene。

3、 Pharmacological action of pangdahai

1. purgative effect
Fat sea seed extract has a laxative effect on rabbits, because it can increase the intestinal volume (the increased volume is 8 times that of agar), which is caused by mechanical stimulation. ; 1: The extract of 400000 kernels increased the intestinal peristalsis of rabbits in vitro, and the other two-layer effects were not significant.

2. Depressurization
Fat sea nuts (fat free dry powder) made into 25% solution, intravenous injection, intramuscular injection or oral, can significantly reduce the blood pressure of dogs and cats. Further experiments showed that its hypotensive principle may be related to the central nervous system. Fat sea seed water extract has hypotensive effect on anesthetized dogs, but it has pressor effect on rabbits (the effective amount in rabbits is 10 times larger than that in dogs); ; Both can be sensitized with histamine.

3. other functions
The water-soluble extracts of fat sea skin, soft shell and kernel have certain diuretic and analgesic effects, and kernel is the strongest; None of them had local stimulatory effect. ; After dogs were killed by massive use for 10-15 days, pulmonary congestion, edema and hepatic steatosis were observed; The LD50 of mice was 12.96 g / kg orally. Rabbits were intravenously injected with a large amount (1%2 ml) of fat sea nuts aqueous extract. It can be seen that the breathing stopped first, the heart still beat, and the gastrointestinal surface was very red.