1、 Pharmacopoeia standard of Rhizoma Zingiberis
This product is a processed product of dried ginger.
[preparation method] take dried ginger and scald it with sand according to the scalding method (general rule 0213) until it bulges and the surface is brown.
[character] this product is irregular swelling block with finger like branches. The surface is brownish black or brownish brown. Light bubble, brown black at the edge of the section, brown yellow in the center, fine granular, scattered vascular bundles. It is fragrant and special, with slight pungent and spicy taste.
[identification] (1) the powder of this product is brown. The starch granules are numerous, long oval, triangular oval, oval, quasi round or irregular, with a diameter of 5-40 μ M. the umbilicus is punctate, located at the smaller end, and there are also cracks, with obvious laminar lines. Gelatinized starch granules and clumps were occasionally seen. Oil cells and resin cells are scattered in parenchyma, containing yellowish oil droplets or dark reddish brown substances. . Ladder shaped conduit, threaded conduit and reticulated conduit are common, and a few are ring shaped conduits with a diameter of 15-70 μ M. Tubular cells containing dark reddish brown substances with a diameter of 12-20 μ M can sometimes be seen near the ducts or fibers.
(2) Take 2G of this product powder, add 20ml of ethyl acetate, sonicate for 10 minutes, filter, and take the filtrate as the test solution. Take another 6-gingerol reference substance and add ethyl acetate to make a solution containing 0.5mg per 1ml as the reference solution. Test according to thin-layer chromatography (general rule 0502), suck 6 μ l each of the above two solutions, dot them on the same silica gel G thin-layer plate, use petroleum ether (60 ~ 90 ℃) - trichloromethane ethyl acetate (2:1:1) as the developing agent, develop, take out, air dry, spray vanillin sulfuric acid test solution, heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, spots with the same color appear at the corresponding position of the chromatogram of the control sample.
[inspection] the moisture content shall not exceed 12.0% (the fourth method of general rule 0832).
The total ash content shall not exceed 7.0% (general rule 2302).
[extract] according to the hot leaching method under the determination method of water-soluble extract (general rule 2201), it shall not be less than 26.0%.
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Chromatographic conditions and system suitability test octadecylsilane bonded silica gel was used as filler; The mobile phase was acetonitrile methanol water (40:5:55); The detection wavelength was 280nm. The number of theoretical plates should not be less than 5000 according to the 6-gingerol peak.
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Preparation of test solution take about 0.25g of powder (passing through No. 3 screen), weigh accurately, place in a corked conical flask, add 20ml of 50% methanol precisely, weigh, sonicate (power 100W, frequency 40KHz) for 30 minutes, cool, weigh again, make up the lost weight with 50% methanol, shake well, filter, and take the filtrate.
The determination method is to precisely suck 8 μ l of the reference solution and 20 μ l of the test solution, inject them into the liquid chromatograph, and determine.
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[nature, taste and meridian tropism] pungent, hot. Return to spleen, stomach and kidney meridians.
[functions and indications] warm meridians to stop bleeding and moderate temperature to relieve pain. For blood loss due to Yang deficiency, vomiting, metrorrhagia, cold due to spleen and stomach deficiency, abdominal pain, vomiting and diarrhea.
[usage and dosage] 3 ~ 9g.
[storage] the same as dried ginger.

2、 Chemical constituents of Rhizoma Zingiberis

Contains volatile components: α - zingiberene, tauraldehyde, catechol, β - myrrhene, nerol, 1,8 cineole, α - terpineolBorneol 、 β - carvaceneLinalool、 ; Spicy ingredients: 4-gingerol, 6-gingerol, 6-gingerol trione, 6-gingerone, etc; A variety of diarylheptanoids: gingerone aCurcumenoneB、CurcumenoneC， .

3、 Pharmacological effects of Rhizoma Zingiberis

1. ginger has anti ulcer effect.

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