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Release Date:2018/3/19 11:04:49
1、 Pharmacopoeia standard of Schisandra chinensis

Schisandra chinensis
Nanwuweizi
SCHISANDRAE SPHENANTHERAE FRUCTUS

. The fruits are picked when they are ripe in autumn, dried in the sun, and the stem and impurities are removed.
[properties] the product is spherical or oblate, with a diameter of 4-6mm. The surface is brownish red to dark brown, dry and wrinkled, and the pulp often clings to the seed. The seeds are 1-2, kidney shaped, brownish yellow on the surface, shiny, and the seed coat is thin and brittle. The flesh is slightly gassy and tastes slightly sour.
[identification] take 1g of this product powder, add 10ml of cyclohexane, sonicate for 30 minutes, filter, evaporate the filtrate, add 2ml of methanol to dissolve the residue, centrifuge, take the supernatant to evaporate, add 1ml of cyclohexane to dissolve the residue, and use it as the test solution. Another 1g of Schisandra sphenanthera reference medicinal material was prepared into the reference medicinal material solution by the same method. Then take the reference substance of anwuzhisu and add cyclohexane to make a solution containing 2mg per 1ml as the reference solution. Test according to thin-layer chromatography (general rule 0502), suck 2 μ l of each of the three solutions, dot them on the same silica gel G thin-layer plate, use chloroform acetone (60:1) as the developing agent, develop, take out, dry, spray phosphomolybdic acid test solution, and heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, there are the same dark blue spots on the corresponding positions of the chromatogram of the control medicinal material and the chromatogram of the control sample.
[inspection] impurities shall not exceed 1% (general rule 2301).
The moisture content shall not exceed 12.0% (the fourth method of general rule 0832).
The total ash content shall not exceed 6.0% (general rule 2302).
[content determination] determine according to high performance liquid chromatography (general rule 0512).
Chromatographic conditions and system suitability test octadecylsilane bonded silica gel was used as filler; Tetrahydrofuran water (38:62) was used as mobile phase; The detection wavelength was 254nm. The number of theoretical plates should not be less than 3000 according to the peak of schisandrin a.
Preparation of reference solution take an appropriate amount of schisandrin ester a reference substance, accurately weigh it, add methanol to make a solution containing 40 μ g per 1ml.
Preparation of test solution take about 0.5g of powder (passing through No. 3 screen), weigh accurately, place in a corked conical flask, add 50ml of methanol precisely, weigh, sonicate (power 250W, frequency 40KHz) for 30 minutes, cool, weigh again, make up the weight lost with methanol, shake well, filter, and take the filtrate.
The determination method is to precisely suck 20 μ l of the reference solution and 20 μ l of the test solution, inject them into the liquid chromatograph, and determine.
According to the calculation of dried product, the content of schisandrin a (c30h32o9) shall not be less than 0.20%.
Decoction pieces
[processing] Schisandra chinensis to remove impurities. Mash when needed.
[character], [identification], [inspection] (moisture and total ash) [content determination] is the same as that of medicinal materials.
Vinegar South Schisandra chinensis take out the South Schisandra chinensis and steam it to black according to the vinegar steaming method (general rule 0213). Mash when needed.
This product is shaped like Schisandra chinensis, and its surface is brownish black, oily, and slightly shiny. It has a slight vinegar aroma.
[identification], [inspection] (moisture and total ash) [content determination] is the same as that of medicinal materials.
[nature, taste and meridian tropism] sour, sweet and warm. Return to lung, heart and kidney meridians.
. It is used for long-term cough, asthenia, sleep loss, seminal fluid, enuresis, frequent urination, continuous diarrhea, spontaneous sweating and night sweating, Tianjin injury and thirst, internal heat and thirst, palpitations and insomnia.
[usage and setting] 2 ~ 6G.
.

2、 Chemical constituents of Schisandra chinensis

It contains volatile oil, such as platycladiene and podophyllene, with high content; In addition, it also contains a variety of lignans, triterpenoid acids, β - elemene glycosides, α - santalene, deoxyschisandrinSchisandra chinensis ester aSchisandrin ethyl ester.

3、 Pharmacological effects of Schisandra chinensis (Turcz.) Baill.The pharmacological effects of Schisandra chinensis (Turcz.) Baill..the research of Schisandra chinensis (Turcz.) Baill.The research on the pharmacological effects of Schisandra

In recent years, Schisandra chinensis polysaccharide has been found to have the effects of protecting liver, anti-aging, anti hypoxia and increasing body immunity. It can excite the central nervous system and directly excite the respiratory center; ; It can strengthen the contractility of the heart, regulate the cardiovascular system and improve blood circulation; It can excite the uterus, strengthen the uterine rhythmic contraction, and has obvious antitussive and expectorant effects; Schisandrin B and other components have a certain protective effect on hepatocytes.
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