1、 Perrin pharmacopoeia standard
 
This product is the dry aerial part of Eupatorium fortunei turcz., a composite plant. Harvest twice in summer and autumn to remove impurities and dry in the sun.
[character] the stem of this product is cylindrical, 30-100cm long, 0.2-0.5cm in diameter; the surface is yellowish brown or yellowish green, some are purplish, and there are obvious nodes and longitudinal edges; It is brittle in texture, and the section pulp is white or hollow. The leaves are opposite, petiolate, and the leaves are mostly shrunk and broken, green brown; ; Those that do not divide are oval, oval lanceolate or oval after flattening. It smells fragrant and tastes slightly bitter.
[identification] (1) the leaf surface of this product: the vertical wall of the upper epidermal cells is slightly curved; The lower epidermal cell wall is wavy and curved, and occasionally non glandular hairs are seen, consisting of 3-6 cells, up to 105 µ m long; the non glandular hairs on the leaf veins are long, consisting of 7-8 cells, 12o-160 µ m long. The stomata are indeterminate.
(2) Take 1g of this product powder, add 15ml of petroleum ether (30-60 ℃), sonicate for 10 minutes, filter, volatilize the filtrate, add 1ml of petroleum ether (30-60 ℃) to dissolve the residue as the test solution. Another 1g of Perrin reference drug was taken and prepared into the reference drug solution by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 5 µ l of each of the above two solutions, dot them on the same silica gel G thin-layer plate, use petroleum ether (30 ～ 60 ℃) - ethyl acetate (19:1) as the developing agent, develop, take out, air dry, spray vanillin sulfuric acid test solution, heat until the spots are clear. .
[inspection] the moisture content shall not exceed 11.0% (the fourth method of general rule 0832).
The total ash content shall not exceed 11.0% (general rule 2302).
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Decoction pieces
[processing] remove impurities, wash, moisten slightly, cut into sections, and dry.
This product has irregular sections. The stem is cylindrical, with yellowish brown or yellowish green surface, and some are purplish, with obvious nodes and longitudinal edges. The cut pulp is white or hollow. The leaves are opposite, and the leaves are mostly shrunk, broken, and green brown. .
[content determination] the content of volatile oil in the same medicinal material shall not be less than 0.25% (ml/g).
[identification] [inspection] is the same as that of medicinal materials.
[nature, taste and meridian tropism] Xin, Ping. Return to spleen, stomach and lung meridians.
[functions and indications] aromatherapy can relieve dampness, invigorate the spleen and appetizer, and relieve summer heat. It is used for damp and turbid obstruction, epigastric nausea, sweet and greasy mouth, bad breath, salivation, heat and dampness table syndrome, early onset of damp temperature, fever, fatigue, chest tightness and discomfort.
[usage and dosage] 3 ～ 10g.
[storage] store in a cool and dry place.

2、 Chemical constituents of Perrin

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Flowers and leaves containDandelion sterol（taraxasterol），Dandelion sterol acetate（taraxasteryl acetate）， Taraxasteryl palmi Tate, β - geraniol ethanol（β - geraniol palmitate（β-amyrin palmitate），Stigmasterol（stigmasterol），β - sitosterol（β-sitosterol），1-n-octacosanol（1-octacosanol），palmitic acid（palmitic acid）。
Stems and leaves contain fumaric acid,Succinic acid（succinic acid），mannitol（mannitol）。 The aerial part contains lindelofin.
The root contains ningdeluofeine and supine lindelofin

2. Taiwan Peilan contains sesquiterpenoids:Eupatorin(eupatolide), Eupaformononin, 4-hydroxy-2-hydroxymethyl-2-butenoyl eupaformosanin

3、 Pharmacological action of Perrin

1. Perrin volatile oil has inhibitory effect on influenza virus.

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3. the alcohol extract of fresh or dry leaves contains a toxic component with acute toxicity. After administration to rabbits, it can make them anesthetized, even inhibit respiration, slow down heart rate, drop body temperature, hyperglycemia and cause diabetes.

4. oral administration of Perrin can cause estrous arrest and ovulation inhibition in mice. Perrin 100% water decoction can inhibit diphtheria bacilli, Staphylococcus aureus, octococcus, proteus, typhoid bacilli, etc. by tube dilution method. .