1、 Pharmacopoeia standard of hemp seed
Hempseed
Huomaren
CANNABIS FRUCTUS
This product is the dried and mature fruit of cannabis sativa L., a mulberry plant. The fruits are harvested when they are ripe in autumn, removed impurities, and dried in the sun.Huomaren
CANNABIS FRUCTUS
. The peel is thin and brittle, and is easily broken. Seed coat green, cotyledons 2, milky white, oily. The air is weak and the taste is light.
[identification] take 2G of this product powder, add 50ml of diethyl ether, heat and reflux for 1 hour, filter, wash the drug residue with 20ml of diethyl ether, discard the ether solution, add 30ml of methanol to the drug residue, heat and reflux for 1 hour, filter, evaporate the filtrate, add 2ml of methanol to dissolve the residue, and use it as the test solution. In addition, 2G of hemp seed control medicinal material was taken, and the control medicinal material solution was prepared by the same method. . In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
Decoction pieces
.
[identification] the same as medicinal materials.
Stir fried sesame seed Remove the hemp seed and stir fry it according to the clear frying method (general rule 0213) until it is yellowish and fragrant.
[nature, taste and meridian tropism] sweet and smooth. Return to spleen, stomach and large intestine.
[functions and indications] moisten the intestines and relieve constipation. For blood deficiency and fluid deficiency, intestinal dryness and constipation.
[usage and dosage] 10 ~ 15g.
[storage] store in a cool and dry place to prevent heat and moth.
2、 Chemical constituents of hemp seed
Seed containsTrigonelline. It contains about 30% fatty oil, including 59.7% - 62.9% linoleic acid, 14.7% - 17.4% linolenic acid, 8.4% - 14.8% oleic acid, and Zeatin.
3、 Pharmacological effects of hemp seed
1. effects on cardiovascular system hemp kernel tincture was dealcoholized and used as an emulsion. 2G / kg was given to the duodenum of anesthetized cats, and the blood pressure began to slowly drop after half an hour, and then fell to about half of the original level after 2 hours. There was no significant change in heart rate and respiration. The blood pressure of normal rats was also significantly reduced by oral administration of 2 and 10g/kg. . The domestic hemp seed varieties are the same as those produced in India, and their physiological effects are also similar.
2. laxative hemp seed can stimulate the intestinal mucosa, increase secretion, accelerate peristalsis, and reduce the absorption of water by the large intestine, so it has a laxative effect. After intragastric administration of 4 and 8g/kg Maren capsules and 4g/kg Maren Pills for 12 hours, both had laxative effect on mice, and the former had stronger effect; 0.1ml of Maren capsules (1:1, 1:0.5) and Maren Pills (1:1) were injected into the small intestine of toads. After 90 minutes of observation, both of them had the effect of increasing intestinal contents.
3. effect on serum cholesterol 20 adult white rats weighing 190-240g, half male and half female, 10 in each group, half male and half female, were selected for the experiment. According to the weight and serum cholesterol concentration, they were divided into random control group and experimental group. The control group was fed with high-fat diet, and the experimental group was added with 10% dried hemp seed sample in the high-fat diet. The results showed that hemp seed could significantly prevent the increase of serum cholesterol in rats. During the experimental period, the serum cholesterol level was relatively stable for 4 weeks, and was significantly lower than that of the control group at 3 and 4 weeks (p< 0.05).