1、
Millennium health
Qiannianjian
HOMALOMENAE RHIZOMA
This product is the dried rhizome of the Araceae plant Homalomena occulta (lour.) Schott. Excavate in spring and autumn, wash, remove the skin, and dry in the sun.Qiannianjian
HOMALOMENAE RHIZOMA
. It is hard and brittle. The section is reddish brown. There are many and obvious yellow needle like fiber bundles. Compared with the other section, there are many needle like holes and a few yellow needle like fiber bundles. Dark brown shiny oil spots can be seen. It is fragrant, pungent and slightly bitter.
[identification] (1) cross section of this product: some remnants of cork cells, brown. There are large secretory cavities scattered in the basic tissues, which are composed of several layers of cork cells; ; The mucous cells were larger and contained calcium oxalate needle crystal bundles; Calcium oxalate cluster crystals are scattered; The outer tough type and perivascular type of vascular bundle are scattered. The outer tough type of vascular bundle is often accompanied by fiber bundles. A single fiber bundle is rare, and the fiber wall is thick and lignified.
(2) Take LG of the product powder, add 20ml of petroleum ether (60 ~ 90 ℃), sonicate for 20 minutes, cool it, filter it, volatilize the filtrate, and add 1ml of methanol to dissolve the residue as the test solution. In addition, take LG, a control medicinal material of qiannianjian, and prepare the control medicinal material solution by the same method. . In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
[inspection] the moisture content shall not exceed 13.0% (the fourth method of general rule 0832).
The total ash content shall not exceed 7.0% (general rule 2302).
[extract] according to the hot leaching method under the alcohol soluble extract determination method (general rule 2201), using dilute ethanol as solvent, it shall not be less than 15.0%.
[content determination] determine according to gas chromatography (general rule 0521).
Chromatographic conditions and system suitability test db-17 capillary column (crosslinked 50% phenyl-50% methyl polysiloxane as stationary phase) (column length: 30m, inner diameter: 0.25mm, membrane thickness: 0.25 μ m); Programmed temperature rise: the initial temperature is 80 ℃, the temperature rises to 100 ℃ at the rate of 2 ℃ per minute, and the injection port temperature is 280 ℃; The detector temperature is 300 ℃; The split ratio was 5:1. The number of theoretical plates shall not be less than 20000 based on the linalool peak.
Preparation of reference solution take an appropriate amount of linalool reference, weigh accurately, and add ethyl acetate to make a solution containing 0.1mg per 1ml.
Preparation of the test solution take about 2G of the powder (passing the second sieve), weigh it accurately, place it in a corked conical flask, add 20ml of ethyl acetate precisely, close the stopper, weigh it, sonicate (power 180W, frequency 42khz) for 30 minutes, cool it, weigh it again, make up the lost weight with ethyl acetate, shake it well, centrifuge, and take the supernatant.
.
The content of linalool (C10H18O) in this product shall not be less than 0.20% calculated as dry product.
Decoction pieces
.
This product is shaped like a round or irregular piece. The outer skin is yellowish brown to reddish brown, rough, some of which can be seen as round root marks, and the cut surface is reddish brown, with numerous yellow fiber bundles, some of which are needle shaped. It is fragrant, pungent and slightly bitter.
[inspection] the total ash content is the same as that of medicinal materials, and shall not exceed 6.0%.
[identification] (except the cross-section) [inspection] (moisture) [extract] [content determination] are the same as that of medicinal materials.
[nature, taste and meridian tropism] bitter, pungent and warm. Return to liver and kidney channels.
[functions and indications] dispel wind dampness and strengthen muscles and bones. It is used for wind cold dampness arthralgia, cold pain of waist and knee, contracture numbness, muscle and bone flaccidity.
.
.
2、 Chemical constituents of Millennium health
Millennium health contains about 0.69% of the volatile oil, and the identified components include α - pinene, β - pinene, limonene,Linalool(linalool),α - terpineol(α-terpineol), ,Geraniol(geraniol),Eugenol(eugenol), Geranial, β - terpineol, isoborneol, terpinen-4-ol,Pogostemol(patchouli alcohol)。
3、 Pharmacological action of qiannianjian
Antibacterial effect the filter paper plate method test showed that the volatile oil of Millennium health significantly inhibited the growth of Brucella (bovine 544, sheep 16, pig 1330) on the plate.