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Release Date:2017/7/21 14:06:10
Dangyao
1、 Pharmacopoeia standard of dangyao
Dangyao
Dangyao
SWERTIAE HERBA
      This product is the dried whole grass of Swertia pseudochinensis Hara, a Gentianaceae plant. Excavate in summer and autumn, remove impurities and dry in the sun.
      . The stem is square columnar, often with narrow wings, many branches, with a diameter of 1-2.5mm; the surface is yellowish green or yellowish brown with purple, and the nodes are slightly expanded; It is brittle, easy to break, and hollow in section. Leaves opposite, sessile; The leaves are mostly shrunken or broken, and the intact ones are in strip lanceolate shape after flattening, with a length of 2-4cm and a width of 0.3-0.9cm. The apex is acuminate, the base is narrow, and the whole margin. Paniculate cymes slender or axillary. Calyx 5-parted, lobes linear. The Corolla is light blue purple or dark yellow, 5-lobed, with 2 glands at the base of the inner side of the lobe, and long hairs around the glands. . The breath is slight and the taste is bitter.
      [identification] (1) take the fine hairs around the gland at the base of the inner side of the corolla of this product and observe it under the microscope. Tumor like protrusions can be seen on the surface.
      (2) In the chromatogram of [content determination], the chromatographic peaks corresponding to the retention time of the chromatographic peaks of swertiamarin and angelicin reference substance should be presented in the chromatogram of the test article.
      [check] moisture is not   .
      Total ash   .
      [content determination] angelicin   Determine according to high-performance liquid chromatography (general rule 0512).
      Chromatographic conditions and system suitability test   ; Methanol water (20:80) was used as mobile phase; .
      Preparation of reference solution   .
      ; Take about 2G of this product powder (passing through No. 3 screen), weigh it precisely, place it in a corked conical flask, add 50ml of methanol precisely, close the stopper, weigh it, sonicate (power 250W, frequency 40KHz) for 20 minutes, cool it, weigh it again, make up the lost weight with methanol, shake it well, filter it, and take the filtrate.
      Assay   Precisely suck 10 µ l of the control solution and 10 µ l of the test solution respectively, inject them into the liquid chromatograph, and determine.
      According to the calculation of dry product, the content of angelicin (c16h22o9) shall not be less than 0.070%.
      Swertiamarin [1]  Determine according to high-performance liquid chromatography (general rule 0512).
      ; Octadecylsilane bonded silica gel was used as filler; Methanol water (20:80) was used as mobile phase; The detection wavelength was 238nm. The number of theoretical plates should not be less than 3000 according to the swertiamarin peak.
      ; Take an appropriate amount of swertiamarin reference substance, accurately weigh it, add methanol to make a solution containing 60 µ g per 1ml.
      Preparation of test solution   Take about 0.1g of this product powder (passing through No. 3 screen), weigh it precisely, place it in a corked conical flask, add 50ml of methanol precisely, close the stopper, weigh it, sonicate (power 250W, frequency 40KHz) for 20 minutes, cool it, weigh it again, make up the lost weight with methanol, shake it well, filter it, take the filtrate, and obtain [2].
      Assay   Precisely suck 10 µ l of the control solution and 10 µ l of the test solution respectively, inject them into the liquid chromatograph, and determine.
      According to the dry product, the content of swertiamarin (c16h22o10) shall not be less than 3.5%.
      Decoction pieces
      [processing] remove impurities, spray water, moisten slightly, cut into sections, and dry.
      . The root is cylindrical like; The surface is yellow or yellowish brown. The stem is square columnar, often with narrow wings, and some branches can be seen; The surface is yellowish green or yellowish brown with purple, the nodes are slightly expanded, and the cut surface is hollow. Leaves and flowers are mostly broken, and there are 2 glands at the base of the inner side of corolla lobes, with long hairs around the glands. . The breath is slight and the taste is bitter.
      [identification] [inspection] is the same as that of medicinal materials.
      . It belongs to the liver, stomach and large intestine.
      [functions and indications] clear dampness and heat, and strengthen the stomach. For damp heat jaundice, hypochondriac pain, dysentery abdominal pain, loss of appetite.
      [usage and dosage] 6-12g, children can reduce it.
      [storage] put it in a dry place.


2、 Chemical composition of Angelica sinensis
The whole herb contains 2% - 4% of the medicinal Picroside,Gentiopicroside, gentianine, i.e., gentianine, gentian anthraquinone,oleanolic acid , dangyaosu,IsoorientinIsovitexin,1,3,5,8-tetrahydroxyxanthone, demethylated Angelica xanthone. Also containsSwertide, kudangyao ester glycoside,Picroside

3、
The work lies in strengthening the stomach, clearing away heat and dampness. It mainly treats dyspepsia, gastritis, acute and chronic bacterial dysentery, jaundice, burning eyes, toothache, and aphthous ulcer.
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