White fresh skin
1、       This product is the dried root bark of Dictamnus dasycarpus turcz., a Rutaceae plant. Excavate the roots in spring and autumn, remove the sediment and coarse skin, peel the root skin, and dry it.
      [properties] this product is in a roll shape, 5-15cm long, 1-2cm in diameter, and 0.2-0.5cm thick. Its outer surface is gray white or light gray yellow, with fine longitudinal wrinkles and fine root marks, and often has protruding granular dots; The inner surface is off white with fine longitudinal lines. It is brittle, with dust flying when it is broken. The section is not flat, and it is slightly layered. The outer layer is stripped, and small bright spots can be seen in the light. It has mutton smell and tastes slightly bitter.
      [identification] (1) cross section of this product: the cork layer is more than 10 rows of cells. The inner layer of the plug is narrow, the fibers are mostly scattered, yellow, with a diameter of 25-100 µ m, thick wall, and obvious lamination. The phloem is broad and the rays are 1-3 rows wide; Fibers are scattered individually. Most calcium oxalate cluster crystals with a diameter of 5-30 µ m are found in the parenchyma.
      (2) Take 1g of this product powder, add 20ml of methanol, sonicate for 30 minutes, filter, evaporate the filtrate, add 1ml of methanol to dissolve the residue, and use it as the test solution. In addition, take the Phellodendron reference substance and fraxinone reference substance, add methanol to make a mixed solution containing 1mg each in 1ml as the reference solution. According to the test of thin-layer chromatography (general rule 0502), suck 5 µ l each of the above two solutions, dot them on the same silica gel G thin-layer plate, use toluene cyclohexane ethyl acetate (3:3:3) as the developing agent, develop, take out, dry, spray with 5% vanillin sulfuric acid solution, and heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, spots with the same color appear at the corresponding position of the chromatogram of the control sample.
      [check] moisture   Not more than 14.0% (the second method of general rule 0832).
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      [content determination] determine according to HPLC (general rule 0512).
      Chromatographic conditions and system suitability test   Octadecylsilane bonded silica gel was used as filler; Methanol water (60:40) was used as mobile phase; The detection wavelength is 236nm. The theoretical number of fraxinone peaks should not be less than 3000.
      Preparation of reference solution   Take an appropriate amount of fraxinone reference substance and Phellodendron reference substance, weigh accurately, add methanol to make a solution containing 60 µ g of fraxinone and 0.1mg of Phellodendron per 1ml.
      Preparation of test solution   Take about 1g of the crude powder of this product (passing through No. 4 screen), weigh it accurately, place it in a conical flask with a stopper, add 25ml of methanol precisely, weigh it, heat and reflux for 1 hour, cool it, weigh it again, make up the lost weight with methanol, shake it well, filter it, and take the filtrate.
      Assay   Precisely suck 10 µ l of the control solution and 10 µ l of the test solution respectively, inject them into the liquid chromatograph, and determine.
      Calculated as a dry product, the content of fraxinone (c14h16o3) shall not be less than 0.050%, and that of berberine (c26h34o7) shall not be less than 0.15%.
      Decoction pieces
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      This product is irregular thick film. ; The inner surface is off white with fine longitudinal lines. The cut surface is white and slightly laminated. It has mutton smell and tastes slightly bitter.
      [identification] (except for the transverse section) [inspection] [extract] [content determination] is the same as that of medicinal materials.
      [nature, taste and meridian tropism] bitter, cold. Return to spleen, stomach and bladder channels.
      [functions and indications] clear away heat and dampness, expel wind and detoxify. It is used for damp heat sores, yellow water dripping, eczema, rubella, scabies, scabies, rheumatism, heat arthralgia, jaundice and red urine.
      [usage and dosage] 5 ～ 10g. For external use, use appropriate amount, wash in decoction or apply with powdered powder.
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2、 Chemical constituents of Dictamnus angustifolia
1. the aboveground part of white delicious rice containsPsoralen（psoralen），Zanthoxylin（xanthotoxin），Scopoletin Pavilion（scopoletin），quercetin （quercetin），Isoquercitrin（isoquercetin）， Root containsDictamnine（dictamnine），Piperine（γ-fagarine），Procyanidine（preskimmianine）］，Colocasine（skimmia-＿nine）， Dasycarpamin, trigonelline, choline, o-ethylnordictamnine, o-ethylnor - γ - fagarine, o-ethylnorskimmianine,Isospeckled zerine（isomaculosidine），Evodiamine（rutaevin）， Dictamnol, peregnenolone,Fraxinellone （fraxinellone），Berberine（obacunone），Limonin（limonin），β - sitosterol（β-sitosterol），Campesterol（campesterol）， Saponins et al.

2. the root bark of Dictamnus angustifolia containsFraxinellone ，Berberine，LimoninLimonindiosphenol and dictamdiol.

3、 Pharmacological effects of dictamni
1. antibacterial effect
2. impact on cardiovascular system and blood
3. effects on uterine and intestinal smooth muscle
4. anticancer effect
5. Dictamnusalbusl. root bark has antipyretic effect