Angelica dahurica
1、 Pharmacopoeia standard of Angelica dahurica       This product is Angelica dahurica (fisch.ex hoffm.) benth.et hook.f. or angelica dahurica (Hangzhou), an umbrella plant.The product is made of Angelica dahurica (fisch.ex Hoffm.)))))the product is made of Angelica dahurica (fisch.ex Hoffm.)the product is made of Angelica dahurica (fisch.ex Hoffm Angelica dahurica（Fisch.ex Hoffm.）Benth.et Hook.f.var.formosana（Boiss.）Shan et Yuan Dried roots of. When the leaves are yellow in summer and autumn, they shall be dug to remove fibrous roots and sediment, and dried in the sun or at low temperature.
      [properties] this product is long conical, 10-25cm long, 1.5-2.5cm in diameter. Its surface is grayish brown or yellowish brown, and its root head is blunt tetragonal or nearly circular, with longitudinal wrinkles, root marks and lenticel like transverse protrusions, and some are arranged in four longitudinal rows. There are hollow stem marks on the top. It is solid, white or grayish white in cross section, powdery, brown in cambium ring, nearly square or nearly round, with most brown oil spots scattered on the skin. It is fragrant, pungent and slightly bitter.
      [identification] (1) the powder of this product is yellowish white. ; The compound granules are mostly composed of 2-12 fractions. The diameter of reticulated conduit and threaded conduit is 10-85 µ M. the cork cells are polygonal or rectangular, yellowish brown. Most of the oil pipes have been broken, containing yellowish brown secretions.
      (2) Take 0.5g of this product powder, add 10ml of diethyl ether, soak for 1 hour, shake constantly, filter, volatilize the filtrate, add 1ml of ethyl acetate to dissolve the residue as the test solution. Another 0.5g of Angelica dahurica reference medicinal material was prepared into the control medicinal material solution by the same method. Then take imperatorin control and isoimperatorin control, add ethyl acetate to make a mixed solution containing 1mg per 1ml as the control solution. Test according to thin-layer chromatography (general rule 0502), suck 4 µ l of each of the above three solutions, dot them on the same silica gel G thin-layer plate respectively, use petroleum ether (30 ~ 60 ℃) - diethyl ether (3:2) as the developing agent, develop them below 25 ℃, take them out, dry them, and view them under ultraviolet light (365nm). In the chromatogram of the test sample, fluorescent spots of the same color appear at the positions corresponding to the chromatogram of the control medicinal material and the chromatogram of the control sample.
      [check] moisture   Not more than 14.0% (the fourth method of general rule 0832).
      Total ash   Not more than 6.0% (general rule 2302).
      [extract] according to the hot leaching method under the determination of alcohol soluble extract (general rule 2201), dilute ethanol shall be used as solvent, which shall not be less than 15.0%.
      [content determination] determine according to HPLC (general rule 0512).
      Chromatographic conditions and system suitability test   ; Methanol water (55:45) was used as mobile phase; .
      Preparation of reference solution   Take an appropriate amount of imperatorin reference substance, weigh accurately, add methanol to make a solution containing 10 µ g per 1ml.
      Preparation of test solution   Take about 0.4g of this product powder (passing through No. 3 screen), weigh it accurately, put it into a 50ml volumetric flask, add 45ml of methanol, sonicate (power 300W, frequency 50KHz) for 1 hour, take it out, cool it, add methanol to the scale, shake it well, filter it, and take the filtrate.
      Assay   .
      The content of imperatorin (c16h14o4) in this product shall not be less than 0.080% calculated as dry product.
      Decoction pieces
      .
      . The outer skin is grayish brown or yellowish brown. The cut surface is white or gray white, powdery, and the cambium is brown, nearly square or nearly round, with most brown oil spots scattered on the skin. It is fragrant, pungent and slightly bitter.
      [check] total ash   No more than 5.0% for the same medicinal materials.
      [identification], [inspection], (moisture), [extract], [content determination] are the same as those of medicinal materials.
      [nature, taste and meridian tropism] pungent, warm. .
      [functions and indications] it can relieve external cold, dispel wind and relieve pain, dredge nasal orifices, stop dampness, relieve swelling and discharge pus. It is used for cold and headache, brow and bone pain, nasal congestion and runny nose, epistaxis, nasopharynx, toothache, band down, sore swelling and pain.
      [usage and dosage] 3 ～ 10g.
      [storage] store in a cool and dry place to prevent moths.


2、 Chemical constituents of Angelica dahurica
1. Hangzhou white peony root containsImperatorin（imperatorin)，Isoimperatorin（isoimperatorin)， Alloisoimpera Torin,Bieouqianhusu（alloimperatorin)，Oxypraeruptorin（oxypeucedanin)， Isooxypeucedanin,oxypeucedanin hydrate （oxypeucedaninhydrate)，Angelica sinensis（byakangelicin)，Angelica sinensis brain（byakangelicol)，Neoangelica sinensis brain（neobyakangelicol)，Coralline（phellopterin)，Zanthoxyl（xanthotoxol)，Bergamot lactone（bergapten)， 5-methoxy-8-hydroxypsoralen, 8-methoxy-4-oxy - (3-methyl-2-butenyl)Psoralen（cnidilin)， A variety of coumarins such as pabulenol [1-3]. Also containsβ - sitosterol（β-sitosterol)，palmitic acidPalmiticid) and calcium, copper, iron, zinc, manganese, sodium, phosphorus, nickel, magnesium, cobalt, chromium, molybdenum and other elements, while the content of sodium, magnesium, calcium, iron and phosphorus is relatively high [4].

2. Radix Angelicae dahuricae contains coumarins:Imperatorin，Isoimperatorin，Oxypraeruptorin，oxypeucedanin hydrate [5]，Coralline; Coumarin glucosides;Praeruptorin（nodakenin)， 3-hydroxy-marmesinin, tert-o-d-glu-copyranosylbyakangelicin, sec-o- β - d-glucopyranosylbyakangeliein,Scopoletin（scopolin)[7]，Icariin（skimmin)， Zanthoxyl-8-o - β - d-glucopyranosylxanthotoxol, tert-o - β - D-glucopyranosyl heraclenol [8], and adeno sine [7].

3、 Pharmacological effects of Angelica dahurica
1. anti inflammatory effect
2. antipyretic and analgesic effects
3. antispasmodic effect
4. cardiovascular effects
5. antibacterial effect
6. photosensitization
7. anticancer effect
8. anti radiation effect
9. other functions