Mullein glycosideAlso known as ergosterol, Mullein, alkosideCimicifugin likeAt present, maorui glycoside has been studied to have anti-inflammatory, immune enhancing, anti hypoxia, anti-cancer and other effects.
Mullein has a protective effect on SHSY5Y induced by 1-methyl-4-phenylpyridine ion (mpp+). Studies have shown that the pathogenesis of Parkinson's disease is related to apoptosis. The protective effect of Mullein on mpp+ induced dopaminergic neuron damage may have the potential effect of anti Parkinson, which may bring new hope for the clinical treatment of neurodegenerative diseases. At the same time, Mullein has inhibitory effect on liver, lung, stomach and other cancer cells.
In addition to the above pharmacological effects, experiments have proved that Mullein glycosides can also prevent and treat osteoporosis.
Osteoporosis is a common metabolic bone disease, which is characterized by progressive loss of bone mass, degeneration of bone microstructure, increased bone fragility and prone to fracture. At present, the main clinical treatment for osteoporosis is estrogen replacement therapy (apoptosis), but long-term use of estrogen may increase the risk of breast cancer, endometrial and cardiovascular disease. It has become a hot spot in modern medicine research to screen and extract natural effective anti osteoporosis components from natural plants. Some preliminary experimental studies have reported that Mullein glycoside can promote the expression of BMP-2 gene in rat osteoblasts, suggesting that Mullein glycoside may have the effect of preventing and treating osteoporosis.