1、 Pharmacopoeia standard of Tongguanteng This product is the dried stem of Marsdenia tenacissima (roxb.) Wight et arn., a plant of Asclepiadaceae. Harvested in autumn and winter, dry.
[properties] this product is oblate cylindrical, slightly twisted, with a diameter of 2-5cm; the nodes are swollen, and there is an obvious longitudinal groove on both sides of the node, which is cross symmetrical at the node. The surface is grayish brown and rough; Cork is soft and slightly thick. It is hard and tough, and it is hard to break a thick one. The section is uneven, often in the shape of "8", with light gray skin and yellow white wood, densely covered with pinhole like pores. The medulla is often hollow. It tastes bitter and sweet.
. The stone cells are yellow, polygonal, quasi circular, quasi square or oval, with a diameter of 35-100 μ m, narrow lumen and obvious pore groove. The cortical fibers were 12-35 μ m in diameter, with thick walls and narrow cell cavities. The wood fiber is yellow, the wall is slightly thick, and the wooden pits are obvious. Pale yellow milk lumps can be seen in the milk ducts. Calcium oxalate has many clusters with a diameter of 12 ～ 30 μ M. The ducts are marginal pit ducts and reticulate ducts with a diameter of 30-200 μ M.
(2) . Another 1g of Tongguanteng reference medicinal material was prepared into the reference medicinal material solution by the same method. Then take the reference substance of Tongguanteng h and add chloroform to make a solution containing 0.5mg per 1ml as the reference solution. According to the thin-layer chromatography (general rule 0502), suck 5 μ l of each of the above three solutions, dot them on the same silica gel G thin-layer plate, use chloroform acetone methanol (20:1:1) as the developing agent, develop, take out, dry, spray vanillin sulfuric acid test solution, and heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, the same yellow spots appear at the corresponding positions of the chromatogram of the control medicinal material and the chromatogram of the control sample.
[inspection] the moisture content shall not exceed 10.0% (the second method of general rule 0832).
.
.
Chromatographic conditions and system suitability test octadecylsilane bonded silica gel was used as filler; Acetonitrile water (50:50) was used as mobile phase; Evaporative light scattering detector detection. The number of theoretical plates shall not be less than 8000 according to the H peak of guanguanteng.
Preparation of reference solution take an appropriate amount of guanguanteng h reference substance, weigh accurately, add methanol to make a solution containing 0.3mg per 1ml.
Preparation of test solution take about 0.5g of powder (passing through No. 3 screen), accurately weigh it, place it in a corked conical flask, precisely add 50ml of methanol, weigh it, sonicate (power 240W, frequency 40KHz) for 45 minutes, cool it, weigh it again, use methanol to make up the weight lost, shake it well, filter it, accurately measure 25ml of the secondary filtrate, evaporate it to dryness, add methanol to dissolve the residue and transfer it to a 2ml volumetric flask, add methanol to dilute it to the scale, shake it well, filter it, and take the secondary filtrate.
The determination method is to accurately suck 10 μ L and 20 μ l of the reference solution and 20 μ l of the test solution, inject them into the liquid chromatograph, determine, and calculate with the external standard two-point method logarithmic equation.
According to the calculation of dry product, the content of guanguanteng H (c42h66o14) shall not be less than 0.12%.
[sexual hemp and menstruation] bitter, slightly cold. Return to lung meridian.
[functions and indications] relieve cough and asthma, expectorant, unblock milk, clear away heat and detoxify. Used for asthma and expectoration, postpartum milk obstruction, rheumatism swelling and pain, sores and carbuncle.
[usage and dosage] 20 ～ 30g. Suitable for external use.
.

2、 Chemical constituents of Caulis tangguanensis
β - d-xanthopyranoside - (1 → 4) - β - d-pyranoside, 11 α, 12 β acetone dihydroxy guanguantengyuan B, lactitol a, 1- (4-hydroxy-3-methoxy-phenyl) - 2 - {2-methoxy-4 - [1 - (E) - propen-3-ol] - phenoxy} - propane-1,3-diol (erythro), galactitolScopoletin, straight milk vegetable disaccharideCarotene, succinic acid

3、 Pharmacological effects of Tongguanteng

1. Treatment of pharyngitis
Tongguanteng can clear away heat, detoxify, and relieve inflammation and pain. It has a good therapeutic effect on human high-risk pharyngitis. It can eliminate pharyngeal inflammation and relieve sore throat. When necessary, you can grind the leaves of fresh Kuteng and take out the juice, add honey to taste and then take it.

2. Treatment of lung heat cough and asthma
Lung heat cough and asthma is a high-risk disease in winter. After it occurs, people will not only feel dyspnea, but also have adverse symptoms such as cough and uncomfortable expectoration. At this time, it can also be treated with Tongguanteng. The dried leaves of Tongguanteng can be fried and drunk. You can drink it many times a day, you can clear lung heat, and the symptoms of cough and asthma can be alleviated quickly.

3. Treatment of milk obstruction
Tongguanteng can also treat milk blockage. When women have no milk or little milk after childbirth, they can be treated with Tongguanteng. During treatment, you can take 20g of Tongguanteng and put it in a bag, stew it with water together with a pig's hoof, and then eat the pig's hoof and drink soup once a day, which can effectively promote milk secretion.

4. Treatment of sores and boils
Tongguanteng, a traditional Chinese medicine, can reduce swelling and pain. It can be used in the treatment of human sores and boils. During the treatment, fresh Tongguanteng can be ground into powder and made into mud, and then applied externally on the part with sores and boils. Changing the dressing once a day can quickly reduce the swelling and pain caused by sores and boils.