1、 Pharmacopoeia standard of Polygonum multiflorum Thunb
This product is the dried vine stem of Polygonum multiflorum thumb. Harvest in autumn and winter, remove the residual leaves, bundle them into bundles or cut them into fresh sections and dry them.
[properties] the product is long cylindrical, slightly twisted, branched, of different lengths, with a diameter of 4-7mm. The surface is purplish red or purplish brown, rough, with twisted longitudinal wrinkles, the nodes are slightly expanded, with side branch marks, and the outer skin is thin, which can be peeled off. . The segmenter is a cylindrical segment. The outer surface is purplish red or purplish brown, the cut skin is purplish red, the wood is yellowish white or light brown, the duct hole is obvious, and the pulp is loose and white like. It is slightly bitter and astringent.
[identification] (1) cross section of this product: epidermal cells sometimes remain. . The cortex is narrower. The fiber bundles of the columella are intermittently arranged in rings, and the fiber wall is very thick and lignified; There are stone cell groups between fiber bundles. Phloem is wider. The cambium forms a ring. Xylem vessels are round in shape, with a diameter of about 204 μ m, and are scattered or clustered in a few. The medulla is smaller. Parenchyma cells contain calcium oxalate clusters.
(2) Take 0.25g of this product powder, add 50ml of ethanol, heat and reflux for 1 hour, filter, and concentrate the filtrate to 1ml as the test solution. Another 0.25g of Caulis Polygoni Multiflori reference medicinal material was taken, and the reference medicinal material solution was prepared by the same method. Then take the emodin control sample and add ethanol to make a solution containing 0.5mg per 1ml as the control solution. According to the test of thin-layer chromatography (general rule 0502), suck 2 μ l of each of the above three solutions, dot them on the same silica gel h thin-layer plate, use the upper solution of petroleum ether (30 ～ 60 ℃) - ethyl formate formic acid (15:5:1) as the developing agent, develop, take out, dry, and view under the ultraviolet light (365nm). In the chromatogram of the test sample, fluorescent spots of the same color are displayed at the positions corresponding to the chromatogram of the control medicinal material and the chromatogram of the control sample; .
[inspection] the moisture content shall not exceed 12.0% (the second method of general rule 0832).
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. Determine according to high-performance liquid chromatography (general rule 0512).
Chromatographic conditions and system suitability test octadecylsilane bonded silica gel was used as filler; Acetonitrile water (26:74) was used as mobile phase; The detection wavelength was 320nm.
The number of theoretical plates shall not be less than 2000 according to the peak of 2,3,5,4 'tetrahydroxystilbene glucoside.
Preparation of reference solution take an appropriate amount of 2,3,5,4 '- tetrahydroxystilbene-2-o - β - D-glucoside reference substance, accurately weigh it, add dilute ethanol to make a solution containing 50 μ g per 1ml.
Preparation of test solution take about 0.5g of the powder (passing through No. 4 screen), accurately weigh it, place it in a corked conical flask, precisely add 25ml of dilute ethanol, weigh it, heat and reflux for 30 minutes, cool it, weigh it again, make up the lost weight with dilute ethanol, shake it well, filter the supernatant, and take the continued filtrate.
The determination method is to precisely suck 10 μ l of the reference solution and 10 μ l of the test solution, inject them into the liquid chromatograph, and determine.
According to the calculation of dry product, the content of 2,3,5,4 '- tetrahydroxystilbene-2-o - β - D-glucoside (c20h22o9) shall not be less than 0.20%.
Decoction pieces
[processing] remove impurities, wash, segment and dry.
This product is a cylindrical segment. The outer surface is purplish red or purplish brown. The cut skin is purplish red, the wood is yellowish white or light brown, the duct hole is obvious, and the pulp is loose and white. It is slightly bitter and astringent.
[identification], [inspection], [extract], [content determination] are the same as those of medicinal materials.
. Heart returning and liver meridian.
[functions and indications] nourishing blood and calming nerves, dispelling wind and unblocking collaterals. For insomnia and dreaminess, body pain due to blood deficiency, rheumatism and arthralgia, and skin itching.
[usage and dosage] 9 ～ 15g. Apply appropriate amount externally and wash the affected area with boiling water.
[storage] put it in a dry place.

2、

The stems contain anthraquinones, mainly  Emodin(Emodin)、Chrysophanol(chrysophanic acid, chrysophanol) orEmodin methyl ether(Emodinmono methyl ether)， All of them exist as binding type. The stems and leaves contain a variety of flavonoids, and luteolin-5-o-xyloside has been obtained. It also contains anthraquinones, and has been obtainedEmodin、Emodin methyl ether, emodin-8-o-5-o-xyloside, flavin-8-o - β - D-glucoside; And containsβ - sitosterol。

3、

; The alcohol extract of Polygonum multiflorum Thunb can inhibit experimental hyperlipidemia in rats; It can prevent and treat experimental atherosclerosis; And can promote immune function.

2. according to the report, 49 cases of scabies were treated with single herb of Polygonum multiflorum Thunb. All 44 cases were cured except 3 cases were cured with sulfur ointment and scabieling Ling during external washing with Polygonum multiflorum Thunb. And 2 cases did not adhere to the medication.