1、 Pharmacopoeia standard of semen Platycladi
This product is the dried and mature seed kernel of Platycladus orientalis (L.) Franco, a cypress family plant. Harvest the mature seeds in autumn and winter, dry them in the sun, remove the seed coat, and collect the seed kernel.
[properties] the product is long oval or long oval, 4-7mm long, 1.5-3mm in diameter. The surface is yellowish white or light yellowish brown, covered with membranous endosperm, the top is slightly pointed, there are dark brown dots, and the base is blunt. It is soft and oily. .
[identification] the powder of this product is dark yellow to brown. The epidermal cells of seed coat are long strip-shaped and often connected with the lower coat cells containing brown pigment. Endosperm cells are polygonal or round, and the lumen is filled with large aleurone particles and fatty oil droplets, and grid like traces are left after aleurone particles dissolve. Cotyledon cells were rectangular, and the cell cavity was filled with smaller aleurone particles and fatty oil droplets.
[inspection] the rancidity shall be determined according to the rancidity determination method (general rule 2303). The acid value shall not exceed 40.0.
Carbonyl value shall not exceed 30.0.
The peroxide value shall not exceed 0.26.
Aflatoxin was determined according to the aflatoxin assay (general rule 2351). The content of aflatoxin B1 should not exceed 5 μ g per 1000g, and the total amount of aflatoxin G2, aflatoxin G1, aflatoxin B2 and aflatoxin B1 should not exceed 10 μ G.
Decoction pieces
[processing] remove impurities and residual seed coat of cypress seed.
[character], [identification], [inspection] are the same as medicinal materials.
Cupressus seed cream take the pure Cupressus seed and make the cream according to the frost making method (general rule 0213).
This product is a uniform, loose light yellow powder, slightly oily, slightly fragrant.
[inspection] the same as that of medicinal materials.
[nature, taste and meridian tropism] sweet and smooth. Homing, kidney and large intestine meridians.
[functions and indications] it can nourish the heart and calm the mind, moisten the intestines and relieve constipation, and stop sweating. For Yin blood deficiency, insomnia due to asthenia, palpitations, constipation due to intestinal dryness, night sweats due to yin deficiency.
[usage and dosage] 10g.
[storage] store in a cool and dry place to prevent heat and moth.

2、 Chemical constituents of semen Platycladi

The seeds contain about 14% fatty oil. They also contain a small amount of volatile oil and saponins. They contain cedrol0, sitosterol, and diterpenoids: pinusolide, 15-16-bis-nora-13-oxo-seminiflora-8 (17) - en-19 acid [15, 16-bisnor-13-oxo-8 (17) - labden-19-oic acid], 15,16-bis-nora-13-oxo-seminiflora-8 (17), 11e-dien-19-acid [15, 16-bisnor-13-oxo-13-oxo-8 (17), 11e-labdadien-19-oic acid], 14,15,16-trinorscutella-8 (17) - ene-13,19-diacid [14, 15, 16-trisnor-8(17)-labdene-13,19-dioic acid]， It also contains about 14% fatty oil and a small amount of volatile oil and saponin.

3、 Pharmacological effects of semen Platycladi

Baiziren can improve passive gyral learning in mice with damaged forebrain basal nuclei. The basal nuclei of the forebrain on both sides of the mice were injured by heat with electrodes, and the ethanol extract of semen Platycladi was given by gavage 250mg/kg and 500mg/kg daily for 15 days. In the dark avoidance method and the step-down method tests, it was proved that it significantly improved the impairment of memory reproduction and the promotion of memory extinction caused by injury; There was also a tendency to improve the access disorder caused by injury; It has no antagonistic effect on the hypokinesia caused by injury.