Stretchy grass
1、 Pharmacopoeia standard of Shenjincao         This product is the dried whole grass of Lycopodium japonicum thunb., a plant of Lycopodium family. .
        [character]   The stolon of this product is thin cylindrical, slightly curved, up to 2m long and 1 ~ 3mm in diameter. There are yellow white fine roots under it; The erect stem is bifurcated. The leaves are densely distributed on the stem, spirally arranged, wrinkled and curved, linear or needle shaped, 3-5mm long, yellowish green to yellowish brown, hairless, awned at the apex, entire, fragile and broken. It is soft, with light yellow skin and white wood. The air is weak and the taste is light.
        [identification]   (1) Cross section of stem: 1 column of epidermal cells. ; The endothelial layer was not obvious. The columella is a series of parenchymal cells, the xylem bundles are irregular banded or branched, the phloem bundles are staggered, and some cells contain yellowish brown substances.
        (2) Take 1g of this product powder, add 15ml of ether, soak it overnight, filter it, volatilize the filtrate, and dissolve the residue with 1ml of absolute ethanol as the test solution. Take another 1g of the control medicinal material of Strelitzia japonica and prepare the control medicinal material solution by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 5 μ l of each of the above two solutions, dot them on the same silica gel G thin-layer plate, use chloroform methanol (40:1) as the developing agent, develop, take out, dry, spray 5% sulfuric acid ethanol solution, and heat at 105 ℃ until the spots are clear. .
        [check]   Moisture   .
        Total ash   Not more than 6.0% (general rule 2302).
        Decoction pieces
        [processing]   Remove impurities, wash, segment and dry.
        This product has irregular segments, cylindrical stems and slightly curved stems. The leaves are dense on the stem, spirally arranged, wrinkled and curved, linear or needle shaped, yellowish green to yellowish brown, and the apex is awned, entire. The cut skin is light yellow, and the wood is white. The air is weak and the taste is light.
        [identification] (except for the transverse section) [inspection] is the same as that of medicinal materials.
        [nature, taste and meridian tropism]   . It belongs to the liver, spleen and kidney meridians.
        ; . It is used for joint soreness and unfavorable flexion and extension.
        [usage and dosage]   3～12g。
        [storage]   Place in a dry place.


2、 Chemical constituents of Eupatorium sinense
Lycopodine, clavolone, clavatoxin andnicotine; Terpenoids:α - formonol（α-onocerin），Terpineol（lycoclavanol）， Lycoclavanin, serratendiol, diepinediol, 21 epimeratenediol, 16 oxodiepiserratenediol, 16 oxo-21-epimeratenediol, clavatol,Terpineol（lyclaninol）， Diepilycocryptol, 16 oxylycoclavanol and 16 oxylycolanitin, etc; Phytosterols:β - sitosterol,Stigmasterol(stigmasterol) andCampesterolβ - D-glucoside of campesterol, which also containsVanillic acid（vanillic acid），Ferulic acid（ferulic acid）， . Celastrol contains alkaloids such as cernuine, lycocernuine, deoxycernuine, nicotine, etc; Terpenoids: 21 epimelalene diol, melalene diol, 21 epimelalene triol, 16 oxo lycopene triol, di epimelalene diol, α - formonol, 16 oxo-21-epimelalene triol, tohogenol, lycornuic acid A and B; phytosterols:β - sitosterol，Stigmasterol，Campesterol, which also contains Lycopodium flavonoid glycosides

3、 Pharmacological effects of Shenjincao
The water extract of Lycoris radiata has a cooling effect on rabbits with fever caused by subcutaneous injection of subtilis extract; Its active ingredients are lycopene, and clavatoxine, and the toxicity of the latter two is weaker than that of lycopene. Appropriate dose of lycopene can increase the blood pressure of anesthetized cats, and it has also been reported that 30mg / kg intravenous injection can suddenly reduce the blood pressure of anesthetized cats and rabbits; . It can enhance the contractility of frog heart, but weaken the contractility of rabbit heart at 1:50000-400000, and the contraction frequency and ECG have no change. 1: 12500-50000 had excitatory effects on isolated rat and guinea pig small intestine, and the peristalsis of isolated rabbit small intestine was also enhanced. It can excite the uterus of rabbits, rats and guinea pigs. It has a cooling effect on rabbits by intravenous injection of 30-50mg/kg. It had no effect on blood glucose, pupil and terminal red blood cell number in rabbits. No antibacterial and antimalarial effects. The median lethal dose of intravenous injection to mice was 27.58 ± 1.16mg/kg, and that of intraperitoneal injection was 78mg/kg. The poisoning symptoms included hyperactivity, tonic, clonic spasm, paralysis, asphyxia, etc; The poisoning symptoms of rabbits were similar. Injection of 50-200mg / kg into the frog's lymphatic sac can cause uncoordinated muscle movement and paralysis. The toxic dose of clonidine: 0.05g/kg in cats, 0.1-0.2g, kg in rabbits and rats. It has been reported that Lycopodium has the effects of diuresis, enhancing uric acid excretion, and relieving children's spastic urinary retention and constipation. . The dosage of Shenjincao was the same as above, which could prolong the sleep time of pentobarbital sodium in mice, and had no significant effect on the convulsion death caused by strychnine; Anti cocaine enhances its toxic effects.