lily
1、 Pharmacopoeia standard of Lily         This product is the dried fleshy scale leaves of Lilium lancifolium thunb., Lilium brownii f.e.brown var.viridulum baker or Lilium pumilum dc. Excavate in autumn, wash, peel the scales and leaves, scald them in boiling water and dry them.
        [properties] the product is long oval, 2-5cm long, 1-2cm wide, and 1.3-4mm thick in the middle. The surface is yellowish white to light brownish yellow, some are slightly purple, and there are several vertical parallel white vascular bundles. The top is slightly pointed, the base is wide, the edge is thin, microwave like, and slightly inward curved. . The breath is slight, and the taste is slightly bitter.
        [identification] take 1g of this product powder, add 10ml of methanol, sonicate for 20 minutes, filter, and concentrate the filtrate to 1ml as the test solution. Another 1g of Lilium reference medicinal material was taken, and the reference medicinal material solution was prepared by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 10 µ l of each of the above two solutions, dot them on the same silica gel G thin-layer plate, use the upper solution of petroleum ether (60 ～ 90 ℃) - ethyl acetate formic acid (15:5:1) as the developing agent, develop, take out, dry, spray 10% phosphomolybdic acid ethanol solution, heat it until the spots are clear. In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
        [extract] determined according to the cold leaching method under the determination method of water-soluble extract (general rule 2201), it shall not be less than 18.0%.
        Decoction pieces
        ; Remove impurities.
        Honey Lily   Take the lily and stir fry it according to the honey roasting method (general rule 0213) until it is not sticky.
        .
        [nature, taste and meridian tropism] sweet, cold. Heart returning and lung meridian.
        [functions and indications] nourishing Yin, moistening lung, clearing heart and calming mind. It is used for dry cough due to yin deficiency, coughing up blood due to labor, palpitations due to deficiency, insomnia and dreaminess, and trance.
        [usage and dosage] 6 ～ 12g.
        .


2、 Chemical constituents of Lily
Lily bulbs contain regaloside a, D, 3,6 '- o-diferuloylsucrose, 1-o-feruloylglycerol, 1-o-p-coumaroylglycerol, 26-o - β - d-glucopyranosyl-noasaponin-3-o - α - l-rhamnosyl - (1 → 2) - β - d-glucopyranoside [26-o - β - D -glucopyranosylnuatigenin-3-o - α - l-rhamnopyranosyl (1 → 2) - β - d-glucopyranoside], 26-o - β - d-glucopyranosyl-noasaponin-3-o - α - l-rhamnopyranosyl - (1 → 2) - O - [β - D-glucopyranosyl (1 → 4)] - β - d-glucopyranoside

3、 Pharmacological action of Lily
1. antitussive and expectorant effect 1.1. antitussive effect mice were treated with SO2 induced cough method to observe its antitussive effect. The results are shown in Table 2. All have obvious antitussive effects.
1.2. expectorant effect phenol red colorimetry was used. The trachea was finally rinsed with 0.5mlnahco3. The absorbance was measured at 546nm, and the amount of phenol red discharged from the trachea was calculated from the phenol red standard curve. The results are shown in Table 3. All have significant expectorant effects.
2. after sedative mice stopped eating for 8 hours, they were Ig Lily 20g/kg, using semen Zizyphus Spinosae as positive control, blank with normal saline, administered with 40mg/kg sodium pentobarbital IP for 30 minutes, and the time from the disappearance of righting reflex to recovery was taken as the sleep time index. At the same time, the effect of pentobarbital sodium subthreshold dose on sleep rate was observed. .
3. nourishing yin and moistening lung 3.1. the swimming experiment of lung qi deficiency model showed that the swimming time was significantly prolonged when Baihe and voluntaine were given to mice at a dose of 10g/kg Ig and compared with astragalus (10g/kg), and the P values of the three were < 0.001.
3.2 hypoxia tolerance test of hyperthyroidism Yin deficiency model, the mouse model was made with thyroxine 0.3mg/ mouse. Results in the lily plus thyroxine group and the voluntaine plus thyroxine group, the hypoxia tolerance of mice was significantly prolonged, and the P values were p<, respectively; 0.01 and p< 0.001.
3.3. for the load swimming experiment of yin deficiency model caused by adrenal cortex hormone, male mice were selected and divided into normal saline group, prednisolone (40mg/kg/ time) modeling group and drug (ig10g/kg) enhanced pine group. Results Lily had a significant protective effect on adrenal cortical failure (p< 0.001).
3.4. it also has a significant inhibitory effect on the delayed allergic reaction induced by 2,4-dinitrochlorobenzene (DNCB) in mice.
4. strengthening effect 4.1. effect on load swimming in mice igl0g/kg drug in mice, and with normal saline and Ejiao Yangxue oral liquid 0.2ml/10g as positive control. Results Salvia miltiorrhiza significantly prolonged the swimming time of mice (p< 0.001).
4.2. effects on Mice 'resistance to normobaric hypoxia for drugs with ig10g/kg in mice, normal saline was used as blank control and Ejiao Yangxue oral liquid 0.2ml/10g was used as positive control. Results the anti hypoxia time of mice was also significantly prolonged (p< 0.05).
4.3. it has no obvious effect on hypoxia resistance caused by isoproterenol.
5. anticancer effect colchicine contained in this product can inhibit the proliferation of cancer cells.