Rabdosia rubescens
1、       This product is the dry aboveground part of Rabdosia rubescens (hemsl.) Hara, a Labiatae plant. The stems and leaves are harvested and dried in summer and autumn when they are luxuriant.
      [character] the stem base of this product is nearly round, and the upper part is square columnar, with a length of 30 ~ 70cm. The surface is red purple and pilose; . Leaves opposite, petiolate; The leaves are shrunk or broken, and the intact ones are oval or ovoid rhomboid after flattening, with a length of 2-6cm and a width of 1.5-3cm; the apex is sharp or acuminate, the base is wide wedge-shaped, and the edges are coarse serrated; The upper surface is brownish green, the lower surface is light green, and it is sparsely pilose along the leaf vein. Sometimes with flowers, the cymose panicle is terminal, the flowers are small, the calyx is tubular bell shaped, 5-lobed teeth, and the Corolla is two lipped. It is slightly fragrant and tastes bitter and sweet.
      [identification] (1) the leaf surface of this product: the upper epidermal cells are polygonal or irregular; The vertical circumferential wall is unduly curved. . Glandular hairs have 1-2 cells in the head and single cells in the stalk. Non glandular hairs have 1-5 cells and warty processes on the outer wall. The cells of the lower epidermis were irregular in shape, and the vertical circumferential wall was wavy and curved. There are many non glandular hairs, glandular hairs and glandular scales. Air hole straight axis type or indefinite type.
      (2) Take 1g of the product powder, add 30ml of methanol, sonicate for 30 minutes, filter, and concentrate the filtrate to 1ml as the test solution. Another 1g of Rabdosia rubescens reference medicinal material was prepared into the reference medicinal material solution by the same method. Then take oridonin reference substance and add methanol to make a solution containing 1mg per 1ml as the reference solution. According to the thin-layer chromatography (general rule 0502), suck 5 µ l of each of the above three solutions, dot them on the same gf254 thin-layer plate, make them into strips, use dichloromethane ethanol acetone (36:3:1) as the developing agent, develop, take out, air dry, use 30% sulfuric acid ethanol solution, heat it at 105 ℃ for about 5 minutes, and view them under sunlight and ultraviolet light (254nm). In the chromatogram of the test sample, spots of the same color appear at the position corresponding to the chromatogram of the control medicinal material; Under UV light (254nm), spots of the same color appear in the chromatogram of the test sample at the corresponding positions of the chromatogram of the reference medicinal material and the chromatogram of the reference substance.
      [check] moisture   .
      Total ash   Not more than 12.0% (general rule 2302).
      Acid insoluble ash   Not more than 2.0% (general rule 2302).
      .
      [content determination] determine according to HPLC (general rule 0512).
      ; Octadecylsilane bonded silica gel was used as filler; Methanol water (55:45) was used as mobile phase; .
      Preparation of reference solution   Take an appropriate amount of oridonin reference substance, accurately weigh it, add methanol to make a solution containing 60 µ g per 1ml.
      Preparation of test solution   Take about 1g of this product powder (passing through No. 4 screen), weigh it accurately, place it in a corked conical flask, add 50ml of methanol precisely, weigh it, place it for 30 minutes, sonicate (power 250W, frequency 40KHz) for 30 minutes, cool it, weigh it again, make up the lost weight with methanol, shake it well, filter it, and take the filtrate.
      Assay   Precisely suck 10 µ l of the control solution and 10 µ l of the test solution respectively, inject them into the liquid chromatograph, and determine.
      According to the calculation of dry product, the content of oridonin (c20h28o6) shall not be less than 0.25%.
      Decoction pieces
      [processing] remove impurities, segment and dry.
      [nature, taste and meridian tropism] bitter, sweet and slightly cold. It belongs to the lung, stomach and liver channels.
      [functions and indications] heat clearing and detoxification, blood activating and pain relieving. It is used for sore throat, symptomatic lump, snake and insect bite.
      [usage and dosage] 30 ～ 60g. Suitable for external use.
      [storage] put it in a dry place.


2、
The stems and leaves contain 0.05% volatile oil, mainly α - pinene, β - pinene, limonene,Cineole(1,8-cineole)， P-cymene, nonaldehyde, decanal, β -elemene,palmitic acid(palmitic acid) et al. cycasin Oridonin(rubescensin A,oridonin)，Oridonin BRubescensin B, ponicidin), α -amyrin. Ludongnin a, lushanrubescensin a,Ursolic acid(ursolic acid)， XinyangOridonin B(xindongnin A、B)， LushanOridonin B、Rabdosia rubescensPropolinRabdosia rubescens,β - sitosterolβ - sitosterol, β - sitosterol-d-glucoside, 2 α - hydroxyursolic acid, and cycliol.

3、 Pharmacological effects of Rabdosia rubescens
Heat clearing and detoxification; Promoting blood circulation and relieving pain. Main throat swelling and pain; ; Tracheitis; Chronic hepatitis; Rheumatic arthralgia; Snakebite