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Release Date:2017/7/21 10:53:15
Pericarp
1、
Pericarp
Digupi
LYCII CORTEX
      . The roots are dug in early spring or after autumn, washed, peeled and dried.
      [properties] the product is cylindrical or grooved, 3-10cm long, 0.5-1.5cm wide, and 0.1-0.3cm thick. The outer surface is grayish yellow to brownish yellow, rough, with irregular longitudinal cracks, and is easy to flake. The inner surface is yellowish white to grayish yellow, relatively flat, with fine longitudinal lines. It is light, brittle, easy to break, with uneven section, yellowish brown outer layer and gray white inner layer. It tastes slightly sweet and bitter.
      [identification] (1) cross section of this product: the cork layer is more than 4-10 rows of cells, and there is a thick cortex outside. Phloem rays are mostly 1 row wide; Fibers are scattered individually or in 2 to several bundles. .
      (2) . In addition, 1.5g of cortex Rehmanniae reference medicinal material was taken, and the reference medicinal material solution was prepared by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 5 µ 1 each of the above two solutions, dot them on the same silica gel G thin-layer plate, use toluene acetone formic acid (10:1:0.1) as the developing agent, develop them, take them out, dry them, and view them under ultraviolet light (365nm). In the chromatogram of the test sample, fluorescent spots of the same color appear at the position corresponding to the chromatogram of the control medicinal material.
      [check] moisture   .
      Total ash   Not more than 11.0% (general rule 2302).
      Acid insoluble ash   Not more than 3.0% (general rule 2302).
      Decoction pieces
      [processing] remove impurities and residual wood cores, wash, dry in the sun or dry at low temperature.
      [properties] this product is in a tube or groove shape, with different lengths. . The inner surface is yellowish white to grayish yellow, relatively flat, with fine longitudinal lines. It is light, brittle, easy to break, with uneven section, yellowish brown outer layer and gray white inner layer. It tastes slightly sweet and bitter.
      [identification] [inspection] is the same as that of medicinal materials.
      [nature, taste and meridian tropism] sweet, cold. It belongs to lung, liver and kidney meridians.
      [functions and indications] cool blood and remove steam, clear lung and reduce fire. It is used for damp heat due to yin deficiency, night sweat due to bone steaming, cough due to lung heat, hemoptysis, bleeding, internal heat and thirst quenching.
      .
      [storage] put it in a dry place.


2、 Chemical constituents of Cortex Lycii
Alkaloids in root bark:betaine(betaine)[1],kukoamine A (kukoamine a) [2] and 1,2,3,4,7, - pentahydroxy-6-azabicyclo [3.3.0] octane (1,2,3,4,7-pen-hydroxy-6nitro-bicyclo [3,3,0] - octane) and 1,4,7,8-tetrahydroxy-6-azabicyclo [3,3,0] octane (1,4,7,8-tetrahydroxy-6-nitrobicyclo [3,3,0]-octane) [3]. . It also contains organic acids with anti angiotensin I converting enzyme activity: (s) - 9-hydroxy-10e, 12z octadecadienoic acid [(s) - 9-hydroxy-10e, 12z octadecadienoicacid] and (s) 9-hydroxy-10e, 12z, 15z octadecadienoic acid [(s) - 9-hydroxy-10e, 12z, 15z octadecadienoicacid] [6]. It also contains lyciumamide, namely aurantiamideacetae [7], linoleic acid [1]. Linolenicacid, melissicacid, cinnamicacid, sugiol, 5 α - stigmastane-3,6-dione [8],Scopoletin Pavilion(scopoletin) [6], β -sitosterolglucoside [9],Scopoletin PavilionScopoletin [6], β - sitosterol glucosde [9], etc. The root contains n-alkanes with 15-33 carbon atoms, mainly n-tricosane and n-trtriaconane; Long chain alcohols with 18-31 carbon atoms; Cholesterol,Campesterol(campesterol),Stigmasterol(stigmasterol),β - sitosterol,palmitic acid(palmiticacid), OLEICACID [10].

The roots of the same genus Ninggu Lycium barbarum contain alkaloids: atropine and hyoscyamine [11].

3、 Pharmacological effects of cortex Rehmanniae
1. Depressurization
2. antipyretic effect
3. hypoglycemic effect: Digupi Decoction 8g/kg can reduce the blood glucose of normal rabbits by 14% and maintain for about 7-8h].

 
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