Peucedanum Peucedanum is a perennial herb belonging to Peucedanum Umbelliferae. As a traditional Chinese medicine, Peucedanum Peucedanum has the effects of dispersing wind heat, relieving cough and resolving phlegm. It is commonly used in the treatment of cold, headache, cough, asthma and chest tightness. The study shows that Peucedanum praeruptorum C is the main effective component of Peucedanum praeruptorum.

    praeruptorin c It has protective effect on cardiovascular system. It mainly adopts the following mechanisms:

(1) Block calcium channel, relieve coronary artery spasm, reduce afterload and reduce myocardial oxygen consumption; At the same time, it limits intracellular calcium accumulation and mitochondrial calcium accumulation to protect mitochondrial function.

(2) Promote the opening of potassium channels, accelerate cell repolarization, especially in the case of ischemic injury and increase of intracellular calcium, inhibit calcium influx, reduce cell excitability, and directly cause the relaxation of vascular smooth muscle and the decrease of myocardial oxygen consumption

(3) Prevention and treatment of arrhythmia induced by ischemia and other factors by affecting action potential of myocardial cells

(4) Through anti oxygen free radicals and lipid peroxidation, it can maintain the balance of cardiac oxidation-reduction system and reduce lipid peroxidation.

    Praeruptorin is rich in resources in China. Both traditional medicine and modern pharmacology research have shown that it has strong biological activities, especially in cardiovascular aspects, such as antihypertensive, anti heart failure, anti myocardial ischemia and so on. Therefore, further study on its mechanism of action and clear clinical indications will have positive significance for disease prevention and treatment and play a greater economic benefit.