Panax notoginseng is known as the "divine medicine for hemostasis" and has been an important medicine in the Department of Traumatology since ancient times. It is clinically proved that Panax notoginseng is a hemostatic drug with the effect of removing blood stasis, which can stop bleeding without leaving blood stasis. Panax notoginseng can promote blood circulation by inhibiting platelet aggregation and reducing blood viscosity. In addition to its strong hemostatic activity, it can remove the congestion in the body, so as to achieve the hemostatic effect. Therefore, it can be used to treat the bleeding symptoms with congestion. The hemostatic effect of Panax notoginseng can be attributed to its active ingredient - "Panax notoginseng". Panax notoginseng element, also known as Panax notoginseng, is the main hemostatic active component of Panax notoginseng, a traditional Chinese medicine of Acanthaceae.
Experimental findingsPanax notoginsengThe hemostatic activity of Panax Notoginseng Injection is stronger than that of hemostatic cichoric acid. 10% Panax Notoginseng Injection can make platelets stretch pseudopodia, gather, deform and other viscous deformation movements, destroy and partially dissolve platelet cells, and produce degranulation secretory reaction, so as to induce platelets to release platelet factor adenosine diphosphate, calcium ion and other active substances, so as to achieve the hemostatic effect. Panax notoginseng can significantly shorten the coagulation time, prothrombin time, and increase the number of platelets and adhesion rate.
It was found that Panax notoginseng can stop bleeding by affecting endogenous and exogenous coagulation system, shortening thrombin time, increasing prothrombin, and inhibiting platelet aggregation. However, high concentration of Panax notoginseng has certain neurotoxicity, so it is necessary to carry out more clinical experiments and pharmacological research on Panax notoginseng to ensure that it can be safely and effectively put into real life.