XBP1
X-box binding protein 1 (XBP1) is a crucial transcription factor involved in the unfolded protein response (UPR) in the endoplasmic reticulum. It plays a central role in maintaining cellular proteostasis by regulating gene expression essential for protein folding, secretion, and degradation. XBP1 activation is critical for the adaptive response to ER stress and is implicated in various physiological processes and pathologies, including cancer, metabolic diseases, and immune responses.
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