VDR
The Vitamin D Receptor (VDR) is a nuclear receptor protein that mediates the biological actions of 1,25-dihydroxyvitamin D3, the active form of vitamin D. VDR plays a crucial role in calcium and phosphate homeostasis, bone metabolism, and immune system regulation. Found in nearly all tissues, VDR signaling influences cell proliferation, differentiation, and apoptosis, impacting various physiological processes and disease states, including cancer, autoimmune conditions, and cardiovascular health.
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