GLS
Global Longitudinal Strain (GLS) is an advanced echocardiographic parameter that quantifies myocardial deformation, reflecting the overall contractile function of the left ventricle. It measures the percentage change in length of the myocardial segments from end-diastole to end-systole. GLS is a sensitive and reproducible indicator for detecting subclinical left ventricular dysfunction, often preceding changes in ejection fraction. It plays a crucial role in early diagnosis, risk stratification, and monitoring of various cardiac conditions, including cardiomyopathy, valvular heart disease, and cardiotoxicity.