SLC10A1
SLC10A1 (Solute Carrier Family 10 Member 1) encodes the sodium/taurocholate co-transporting polypeptide (NTCP), a key transporter primarily expressed in the liver. NTCP is responsible for the uptake of conjugated bile acids from the portal circulation into hepatocytes, a crucial step in enterohepatic circulation. It also serves as a functional receptor for the hepatitis B virus (HBV) and hepatitis D virus (HDV), mediating viral entry into liver cells. Dysregulation of SLC10A1 is implicated in cholestatic liver diseases and viral hepatitis.
No Data！
