1、 Mianma Guanzhong pharmacopoeia standard. This product is the dry rhizome and petiole residues of Dryopteris crassirhizoma Nakai, a dryopteridae plant. Excavate in autumn, remove petioles, fibrous roots, remove sediment, and dry in the sun.
[properties] this product is long obovate, slightly curved, blunt round or truncated at the upper end, sharp at the lower end, and some are divided into two halves in longitudinal section, 7-20cm long and 4-8cm in diameter. The surface is yellowish brown to dark brown, densely covered with neatly arranged petiole residues and scales, and has curved fibrous roots. ; There are often three fibrous roots on the outside of each petiole residue, and the scales are strip-shaped lanceolate, entire, and often fall off. It is hard, with a slightly flat section, dark green to brown, with 5-13 yellow white vascular bundles, arranged in a ring, and scattered with many leaf trace vascular bundles. The taste is light and slightly astringent at first, and then becomes bitter and pungent.
[identification] (1) the transverse section of the petiole base of this product: the epidermis is a row of small cells with thickened outer wall, which often fall off. The lower skin is composed of more than 10 rows of polygonal thick walled cells, brown to brown, with loose arrangement of basic tissue cells, single-cell interstitial glandular hairs in the intercellular space, and a spherical or pear shaped head containing brown secretions; .
(2) Take 0.5g of the product powder, add 20ml of cyclohexane, sonicate for 30 minutes, filter, take 10ml of the continuous filtrate, and concentrate it to 5ml as the test solution. Another 0.5g of Mianma Guanzhong reference medicinal material was prepared into the reference medicinal material solution by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 4 μ l of the test solution and 5 μ l of the control medicinal material solution, respectively, onto the same silica gel G thin-layer plate [take silica gel g10g, 10ml of citric acid disodium hydrogen phosphate buffer (pH7.0), 60mg of vitamin C, 20ml of sodium carboxymethyl cellulose solution, mix well, lay the plate, dry in the dark at room temperature, activate at 50 ℃ for 2 hours, and then use n-hexane trichloromethane methanol (30:15:1) as the developing agent, pre saturate the thin-layer plate in the developing cylinder for 2 hours, develop it with a span of more than 8cm, take it out, and immediately spray it with 0.3% firm dilute ethanol solution of blue BB salt, placed at 40 ℃ for 1 h. In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
[inspection] the moisture content shall not exceed 12.0% (the second method of general rule 0832).
The total ash content shall not exceed 7.0% (general rule 2302).
Acid insoluble ash content shall not exceed 3.0% (general rule 2302).
[extract] according to the hot leaching method under the alcohol soluble extract determination method (general rule 2201), using dilute ethanol as solvent, it shall not be less than 25.0%.
Decoction pieces
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The product is in irregular thick pieces or fragments. The outer surface of the rhizome is yellowish brown to dark brown, and is mostly covered with petiole residues. Some can see brown scales, the cut surface is light brown to reddish brown, and there are yellowish white vascular bundle dots, arranged in a ring. The taste is light and slightly astringent at first, and then becomes bitter and pungent.
[identification] the powder of this product is light brown to reddish brown. Interstitial glandular hairs are single-cell, mostly broken, and intact ones are oval and quasi round, with a diameter of 15-55 μ m, containing yellowish brown substances. The diameter of the trapezoidal tracheid is 10-85 μ M. The fibers of the lower skin are in bundles or scattered individually, yellowish brown or reddish brown. The starch granules are round in shape, with a diameter of 2 ～ 8 μ M.
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[nature, taste and meridian tropism] bitter, slightly cold; . Return to liver and stomach channels.
[functions and indications] clear away heat, detoxify and expel insects. For insect accumulation, abdominal pain and sores.
[usage and dosage] 4.5 ～ 9g.
[storage] store in a ventilated and dry place.

2、 Chemical constituents of Dryopteris crassipes.

containMianma guanzhongsu ABBA, is the characteristic component of this medicinal material; Filmarone, decomposed to produce: filicacid BBB, PBB, PBP, flavaspidic acid BB, Pb, AB; Albaspidin AA, BB, Pb, etc.

3、 Pharmacological effects of Rhizoma Drynariae.

The pharmacological effects of Mianma Guanzhong are mainly reflected in: it has anthelmintic effect; It has different degrees of bactericidal effect on Staphylococcus aureus, Escherichia coli, fungi and gram negative bacteria; It has the effects of uterine contraction, anti early pregnancy and abortion; . In addition, it has antihypertensive and anti-inflammatory effects.