Small mottle bone
1、 Pharmacopoeia standard of Xiaobo bone       This product is the dry aboveground part of gendarussa vulgaris nees, a plant of the family euonyceae. It can be harvested all year round, removed impurities and dried in the sun.
      [character] the stem of this product is cylindrical with branches, 40 ～ 90cm long and 0.2 ～ 3cm in diameter. The stem surface is yellowish green, light green brown or brownish green, with sparse small yellow lenticels; Branchlets slightly tetragonal, nodes swollen. It is brittle, easy to break, and the section is yellowish white. The leaves are opposite, curled and broken, flattened into narrow lanceolate or strip lanceolate shape, 4 ～ 14cm long and 1 ～ 2cm wide; the apex is acuminate, the base is cuneate, full margin, and the leaf veins are slightly purple. Some spikes can be seen, terminal or in the upper leaf axils, bracts are narrow and thin, and the Corolla is two lipped. Slightly pungent and sour.
      [identification] (1) the powder of this product is yellowish green to yellowish brown. The stone cells are numerous, yellow, with a diameter of 20-80 μ m, and obvious lamination. Glandular scales have 4 cells in the head and single cells in the stalk. Air hole straight axis type or inequality. . The conduits are mostly with marginal pits and threads. The parenchyma cells contained calcium oxalate crystals with a diameter of 2-10 μ M.
      (2) Take 2G of this product powder, add 50ml of ethanol, sonicate for 30 minutes, filter, evaporate the filtrate, add 1ml of ethanol to dissolve the residue, and use it as the test solution. In addition, 2G of the control medicinal material of small barge bone was taken and made into the control medicinal material solution by the same method. According to the test of thin-layer chromatography (general rule 0502), suck 5 μ l of each of the above two solutions, dot them on the same silica gel G thin-layer plate, use petroleum ether (60 ～ 90 ℃) - ethyl acetate (4:1) as the developing agent, develop, take out, dry, spray 10% sulfuric acid ethanol solution, and heat at 105 ℃ until the spots are clear. In the chromatogram of the test sample, spots of the same color appear on the corresponding position of the chromatogram of the control medicinal material.
      [inspection] the moisture content shall not exceed 13.0% (the second method of general rule 0832).
      The total ash content shall not exceed 11.0% (general rule 2302).            
      .
      Decoction pieces
      [processing] remove impurities and cut into sections.
      [nature, taste and meridian tropism] pungent, warm. Return to liver and kidney channels.
      [functions and indications] remove blood stasis and relieve pain, and connect tendons and bones. .
      .
      [note] pregnant women should use it with caution.
      [storage] put it in a dry place.


2、 Chemical constituents of lapis minor
cycasin β - sitosterol（β-sitosterol）。 The root contains alkaloid justicin and volatile oil.

3、
Root decoction or alcohol extract (1-2g/kg) can increase the body temperature of rats; If the dose is too large (10-20g/kg), the body temperature will drop, and the diarrhea will be severe, which will eventually lead to death.