What is corosolic acid

    Corosolic  acid, also known as 2 α - hydroxyursolic acid, is a triterpenoid compound found in crape myrtle (commonly known as Barnabas, which abounds in the Philippines), loquat and other plants.

Pharmacological action of corosolic acid

    The results of in vitro and in vivo experiments show that,corosolic acid By stimulating glucose transport, it can promote the absorption and utilization of glucose by cells, so as to achieve the hypoglycemic effect. The excitatory effect of corosolic acid on glucose transport is similar to that of insulin. Therefore, corosolic acid is also called "plant insulin". The results of animal experiments showed that corosolic acid had a significant hypoglycemic effect on normal rats and hereditary diabetic mice. Corosolic acid also has the effect of weight loss. Clinical studies have found that after taking the drug, it can regulate the content of insulin and blood glucose in the body, with an obvious trend of weight loss (monthly average weight loss of 0.908-1.816Kg). The process is relatively slow and no diet is required. Corosolic acid also has a variety of other biological activities. For example, it has a significant inhibitory effect on TPA induced inflammatory response, and its anti-inflammatory effect is stronger than that of indomethacin; It also has DNA polymerase inhibitory activity and inhibits the growth of a variety of tumor cells. In recent years, it has been found that it has antiviral and anti cardiovascular effects.