Rosmarinicacid (Rosa) is a water-soluble natural phenolic acid compound isolated from rosemary, a Labiatae plant. Due to its strong free radical scavenging activity and antioxidant effect, it has a lot of biological activities. The mechanism of each activity is as follows:

Anti inflammatory activity      
1. it is related to 5-lipoxygenase (  5-LOX), which inhibits arachidonic acid metabolism;  2. complement dependent pgl2  It interferes with the activity of C3 transferase in different pathways;   3. antioxidation and free radical elimination;   4. inhibit histamine release from mast cells.

Antiplatelet aggregation and antithrombotic effect  
Rosmarinic acidIt can inhibit platelet aggregation and enhance plasma fibrinolytic activity.

Antidepressant activity
The release of histamine and no in human brain is the main cause of stress and depression. Rosmarinic acid can inhibit the release of histamine in mast cells, and caffeic acid can activate a adrenoceptor system and inhibit the production and release of No.

antibacterial activity
1.  Significantly increase the permeability of bacterial cell membrane, accelerate the leakage of sugars and proteins, and disorder cell metabolism,And then affect bacterial protein metabolism;   2.  It can also exert its bacteriostatic effect by inhibiting the activity of DNA polymerase and affecting DNA replication.

Antiallergic activity  
By improving the action of cytokines, chemical factors and allergen specific antibodies, it can significantly inhibit skin allergic reactions.

Antiviral activity
In addition to inhibiting the activities of some enzymes in the life cycle of the virus, it can also rapidly bind to the viral coat protein, thereby inactivating the virus.

UV protection  
It can reduce the content of free radicals caused by UV, and also reduce the damage of UV to DNA.   Protective effect on neurons.  

Liver protection  
Rosmarinic acid can reduce the level of intrahepatic peroxide and increase the synthesis of glutamylcysteine in the liver, so it can protect the liver injury and lipid peroxidation caused by peroxide.