Atractylodes macrocephala Koidz is the dry root of atractylodes  macrocephala Koidz, which is a common tonic. Its nature is sweet, bitter and warm. It has the effects of invigorating the spleen and Qi, drying dampness and promoting diuresis, stopping sweating and calming the fetus. Lactones in Atractylodes macrocephala extract are the main active substances, which have anti-inflammatory and anti-tumor effects, and have a certain impact on gastrointestinal function. The above pharmacological activities are especiallyAtractylodes macrocephala lactone IThe activity was the most significant. There are many subtypes of Atractylodes macrocephala lactone, such as Atractylodes macrocephala lactone IAtractylodes Ⅱ, Atractylodes Ⅲ, etc.

1 anti inflammatory effect

    Relevant studies have confirmed that lactones have anti-inflammatory and immunomodulatory functions. They have shown significant efficacy in the prevention and treatment of acute and chronic inflammation, sepsis or abdominal infectious diseases. The role of these lactones is related to the inhibition of inflammatory cells to produce inflammatory factors.

2 anti tumor effect

    Atractylodes macrocephala may regulate tumor apoptosis suppressor gene bcl-nbsp; -  2  And stimulate the immune response regulated by lymphocytes to achieve the antitumor effect

3 Effect on spleen and stomach

    The inhibition of Atractylodes macrocephala lactone Ⅰ and Atractylodes macrocephala lactone Ⅲ on gastrointestinal motility may be due to the inhibition of ca2+ induced gastrointestinal contraction.

4 Effect on muscle

    Bibaizhu lactone can significantly reduce the contractile force of isolated right atrial muscle of guinea pigs and slow down its nodal rate

5. Effect on senile dementia

    Atractylodes macrocephala lactone can effectively improve the learning and memory ability of dementia rats, suggesting that Atractylodes macrocephala lactone can alleviate the intellectual disorder of dementia model rats to a certain extent

6. Anti dust mite effect

   Atractylodes ⅢTherefore, it can be developed as an effective component of air fresheners.