Broccoli is one of the common vegetables in our daily table. It is a kind of cruciferous plant. Its glucosinolates are very rich. The glucosinolates contained in broccoli are mainly radish glucosinolates (4-methylsulfinyl butenyl glucosinolates and 3-methylsulfinyl propenyl glucosinolates). The main degradation product of sulforaphane is sulforaphane. Sulforaphane mainly belongs to isothiocyanate, with high anticancer activity. It is a multifunctional inducer, which can induce the body to produce type II detoxifying enzyme   Glutathione transferase and quinone reductase, which can produce resistance to many carcinogens and thus play an anti-cancer role.SulforaphaneIt is also often found in cruciferous vegetables.

    It has been reported that the degradation products of some glucosinolates can effectively prevent the production of lung cancer, colon cancer, liver cancer and gastric cancer. The mechanism of isothiocyanate preventing and treating a variety of cancers mainly includes inhibiting the activity of phase I reductase and inducing the production of phase II enzyme. The metabolic activation of carcinogens can be blocked by inhibiting the activity of phase I reductase, especially phenethyl isothiocyanate and benzyl isothiocyanate can effectively inhibit the formation of carcinogen DNA adducts, avoid the damage to DNA chain, and thus inhibit the formation of tumor induced by anticancer factors. By inducing the production of phase II enzyme, the concentration of phase II enzyme in the body can be increased, so as to more effectively catalyze the transformation of toxic substances into hydrophilic substances and discharge from the body. In vivo and in vitro experiments of some human tumor cells, some results showed that glucosinolates may also inhibit the formation of tumor cells by inhibiting cell mitosis and promoting apoptosis.

    Cruciferous vegetables are cooked by heating. However, previous studies have found that after cooking, the content of isothiocyanate in cruciferous plants is very low, almost No. Therefore, cruciferous vegetables should be eaten raw as much as possible. Even if they are cooked, the cooking steps should be reduced and their nutrients should be preserved as much as possible. Us b& Dnutritionalingradients has successfully developed broccoli polyphenol vegetarian capsules containing 10% sulforaphane (a kind of natural polyphenols) and mixed enzyme preparations, which take advantage of the characteristics of sulforaphane in vivo to convert into sulforaphane, thus playing a physiological regulation role.