Peony perianth is listed as one of the six famous flowers in China. Paeonia lactiflora has not only high ornamental value, but also important medicinal value. Peony is named "Peony" because of its charming flower shape and gorgeous color, which is the homonym of "Zhang Yue" to describe beautiful appearance. The ancients commented on flowers: peony was the first and peony was the second. It was said that peony was the king of flowers and peony was the appearance of flowers. Because it blooms late, it is also called "Dianchun". But peony is not only a famous flower, but also the root can be used for medicine. According to the analysis, peony root containsPaeoniflorinAnd benzoic acid, with different uses.
The white peony in traditional Chinese medicine mainly refers to the root of peony, which is an antispasmodic, analgesic and menstrual drug. It is effective for women with abdominal pain, stomach spasm, dizziness, gout, diuresis and other diseases. Generally, the root of peony cultivated species is used as white peony. Because its root is hypertrophy and straight, the finished product after processing is of good quality. Wild Peony is only sold as red peony because of its thin root. The red spoon of traditional Chinese medicine is the root of herbaceous peony. It has the effects of dispersing silt, activating blood circulation, relieving pain and purging liver fire. It mainly treats irregular menstruation, phlegm stagnation, abdominal pain, joint swelling and pain, chest pain, rib pain, etc. Paeoniflorin extracted from roots has a variety of pharmacological activities, which has aroused the interest of many researchers.
Paeoniflorin mainly has the following pharmacological effects:
It can dilate blood vessels, protect cerebral ischemia, protect brain edema, blood-brain barrier and local cerebral blood flow after cerebral ischemia, and improve the effect of anti thrombosis caused by high fat and high cholesterol.
2. anti platelet aggregation: platelet aggregation is one of the important "culprits" of various cardiovascular and cerebrovascular diseases. Paeoniflorin inhibited platelet aggregation induced by ADP and collagen in varying degrees.
3. it can also act on the central nervous system, with significant analgesic, sedative and anticonvulsant effects.
4. anti tumor effect. Paeoniflorin can inhibit the activity of ATPase on tumor cell membrane and increase the activity of adenylate cyclase (AC).
5. immune regulation. Paeoniflorin has certain immune regulation function. Human peripheral lymphocytes are one of the main target cells for paeoniflorin to play a role in vivo. Paeoniflorin may promote the excessive proliferation of human peripheral lymphocytes by inhibiting IL-1, restore the balance of th1/th2 cytokines, and play its immunomodulatory role.
6. hypoglycemic effect. Paeoniflorin and 8-debenzoyl paeoniflorin isolated from the root of Paeonia lactiflora can reduce blood glucose in rats. Intravenous injection of paeoniflorin could significantly reduce the blood glucose of streptozotocin induced diabetic mice, and the sugar content in plasma gradually decreased with the prolongation of administration time.
7. antispasmodic effect. Paeoniflorin can relax smooth muscle cells, and the decrease of ca2+ plays an important role in the relaxation of smooth muscle cells. Paeoniflorin may regulate ca2+/na+ Exchange to relax smooth muscle cells. In gastrointestinal smooth muscle cells, membrane potential determines the contractile and diastolic function of gastrointestinal tract by affecting the excitability of smooth muscle cells.