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Release Date:2015/4/17 18:26:02

    Myocardial ischemia is a serious threat to human health. Myocardial ischemia refers to a pathological state in which the blood perfusion of the heart is reduced, resulting in the reduction of oxygen supply to the heart, abnormal energy metabolism of the myocardium, and unable to support the normal work of the heart. Coronary heart disease is the most important and common cause of myocardial ischemia. With the improvement of people's living standards, the prevalence of myocardial ischemia in China is increasing year by year. Myocardial ischemia is a common and frequently occurring disease in the elderly. The harm of myocardial ischemia is very serious. If we do not pay attention to it, timely and effective treatment will lead to more serious potential consequences. Therefore, it is of great practical significance to study the drugs for the treatment of myocardial ischemia.

    In recent years, traditional Chinese medicine (TCM) has attracted much attention because of its good curative effect and small side effects in the treatment of myocardial ischemia. Echinacea glycoside is extracted and isolated from the root of Cistanche tubulosa. It is a phenylethanol glycoside with the highest content in the total glycosides of Cistanche tubulosa, the active part of Cistanche tubulosa. It is a representative compound of this kind in the plant world. Recent studies have shown that the pharmacological effects of ECH mainly include antioxidation, nerve protection, liver protection, anti-inflammatory, anti swelling and pain, learning and memory improvement, and immune regulation. A large number of studies have shown that free radical injury, inflammatory reaction and apoptosis are three important links of myocardial injury; Vascular endothelial system, ion channels and adrenoceptors play an important role in the relaxation and contraction of blood vessels. The mechanism of protective effect of ECH on ischemic myocardium is related to the reduction of oxidative and hypoxic injury of myocardial cells. Inhibition of intracellular calcium overload, reduction of myocardial apoptosis and dilation of blood vessels; It shows a significant role in anti-oxidation damage, and has a trend in anti-inflammatory.

    Echinacea glycosideThe possibility of application in myocardial ischemia is undoubtedly of great economic benefit. If it can be put into actual production, it will greatly promote the prevention and treatment of myocardial ischemia.

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