With the development of science and technology, the efficacy of Chinese herbal extracts has attracted more and more attention of scholars at home and abroad. Through scientific experimental research and careful analysis of the components in the extracts, more and more Chinese herbal medicines have been recognized by international scholars. Bupleurum chinense is a traditional Chinese medicine that has been widely studied by scholars at home and abroad. Recent pharmacological studies have shown that Bupleurum Bupleurum not only has the effects of analgesia, antipyretic, antitussive, anti-inflammatory, anti pathogen, anti ulcer, but also has the functions of protecting the liver and regulating immunity, especially on the cardiovascular system. The analysis of saikosaponin in Bupleurum chinense is particularly important. Saikosaponin is a pentacyclic triterpenoid oleanolane derivative. Experiments show that saikosaponin has a variety of pharmacological activities.

    Up to now, saikosaponin has been widely accepted by the pharmaceutical industry that it has the physiological activities of anti-inflammatory, liver protection, lowering blood cholesterol and blood lipids. With further study, some other physiological activities were found. It mainly includes the following items:

    1. Inhibition of trypsin

    It is found that saikosaponin has a strong inhibitory effect on trypsin, so it can be speculated that saikosaponin may inhibit pancreatic protease in the treatment of acute pancreatitis.

    2. Application of anti hepatic fibrosis

    SaikosaponinThrough its own biological characteristics of anti-inflammatory and immune regulation, it can achieve its intervention in the mechanism of liver fibrosis. Firstly, it can reduce the inflammatory mediators released by hepatic stellate cells, Kofi cells and hepatic sinusoidal endothelial cells through anti-inflammatory effect, so as to prevent their initiation and intensification in the process of liver fibrosis; Secondly, inhibiting the activation of stellate cells plays a key role in anti fibrosis.

    3. Application in the treatment of nephrosis

    Studies have shown that both animal experiments and clinical trials. Saikosaponin has good effects on various nephritis and renal function, which provides a new way to treat this kind of disease. This new therapeutic approach overcomes the toxic and side effects of glucocorticoids and cyclophosphamide cytotoxic drugs on human body.

    4. Inhibitory effect of saikosaponin d on proliferation of different leukemia cells

    5. Anticonvulsant effect

    If the discovery of these new medicinal effects of saikosaponin can be truly applied in clinical practice, it will benefit many patients.