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Home >  TCM Compounds Library > Isorhamnetin

Synonym name: Isorhamnetol; Quercetin 3'-methyl ether
Catalogue No.: BP0794
Cas No.: 480-19-3
Formula: C16H12O7
Mol Weight: 316.265
Botanical Source: Widespread in plants, incl. chives, corn poppy leaves, garden cress, fennel, hartwort, red onions, pears, dillweed, parsley and tarragon. First Cheiranthus cheiri in 1896

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

Inquire for bulk scale.

Typical COA:
               Isorhamnetin-COA.pdf


Reference:

1)Isorhamnetin and astragalin from the leaves of Hippophae rhamnoides
D. B. Rasputina, N. F. Komissarenko and D. Ts. Tsybikova
Chemistry of Natural Compounds, 1976, Volume 12, Number 1, Page 87
2)Simultaneous LC Determination of Quercetin, Kaempferol and Isorhamnetin in Rabbits after Intragastric Administration of an Ethanol Extract from Pollen Typhae
Yu Li, Yan Yang, Shixiang Wang, Yinmao Wei and Xiaohui Zheng
Chromatographia, 2009, Volume 69, Numbers 1-2, Pages 117-121
3)Isorhamnetin protects rat ventricular myocytes from ischemia and reperfusion injury  Original Research Article
Experimental and Toxicologic Pathology, In Press, Corrected Proof, Available online 8 October 2009
Najuan Zhang, Fei Pei, Huaying Wei, Tongtong Zhang, Chao Yang, Gang Ma, Chunlei Yang
4)The flavonoid component isorhamnetin in vitro inhibits proliferation and induces apoptosis in Eca-109 cells  Original Research Article
Chemico-Biological Interactions, Volume 167, Issue 2, 25 April 2007, Pages 153-160
Gang Ma, Chunlei Yang, Yi Qu, Huaying Wei, Tongtong Zhang, Najuan Zhang
5)Isorhamnetin-induced anti-adipogenesis is mediated by stabilization of -catenin protein  Original Research Article
Life Sciences, Volume 86, Issues 11-12, 13 March 2010, Pages 416-423
Jongsung Lee, Jienny Lee, Eunsun Jung, Wangtaek Hwang, Yeong-Shik Kim, Deokhoon Park
6)In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells  Original Research Article
Pharmacological Research, Volume 54, Issue 3, September 2006, Pages 186-194
Bao-song Teng, Yan-Hua Lu, Zheng-Tao Wang, Xin-Yi Tao, Dong-Zhi Wei
7)Isorhamnetin prevent endothelial cell injuries from oxidized LDL via activation of p38MAPK  Original Research Article
European Journal of Pharmacology, Volume 547, Issues 1-3, 10 October 2006, Pages 22-30
Meihua Bao, Yijia Lou
8)Dietary quercetin is recovered in rat plasma as conjugated derivatives of isorhamnetin and quercetin  Original Research Article
The Journal of Nutritional Biochemistry, Volume 7, Issue 7, July 1996, Pages 375-380
Claudine Manach, Odile Texier, Francoise Rgrat, Georgine Agullo, Christian Demign, Christian Rmsy
9)Comparative pharmacokinetics and bioavailability studies of quercetin, kaempferol and isorhamnetin after oral administration of Ginkgo biloba extracts, Ginkgo biloba extract phospholipid complexes and Ginkgo biloba extract solid dispersions in rats  Original Research Article
Fitoterapia, In Press, Corrected Proof, Available online 5 July 2010
Zhi-peng Chen, Jun Sun, Hong-xuan Chen, Yan-yu Xiao, Dan Liu, Jun Chen, Hao Cai, Bao-chang Cai
10)Simultaneous determination of quercetin, kaempferol and isorhamnetin accumulated human beast cancer cells, by high-performance liquid chromatography 
Journal of Pharmaceutical and Biomedical Analysis, Volume 39, Issues 1-2, 1 September 2005, Pages 328-333
Yi Wang, Jiang Cao, Jian-Hua Weng, Su Zeng
11)Separation of quercetin, sexangularetin, kaempferol and isorhamnetin for simultaneous HPLC determination of flavonoid aglycones in inflorescences, leaves and fruits of three Sorbus species  Original Research Article
Journal of Pharmaceutical and Biomedical Analysis, Volume 48, Issue 3, 4 November 2008, Pages 629-635
Monika Olszewska
12)Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD  Original Research Article
Journal of Pharmaceutical and Biomedical Analysis, Volume 41, Issue 3, 7 June 2006, Pages 714-719
Yuangang Zu, Chunying Li, Yujie Fu, Chunjian Zhao
13)Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis  Original Research Article

Cancer Letters, Volume 270, Issue 2, 8 November 2008, Pages 342-353

 

Isorhamnetin

Isorhamnetin



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